Results 61 to 70 of about 78,567 (300)
Animal, 2013 A total of twelve lactating Jersey cows were used in a 5-week experiment to determine the effects of severe feed restriction on the permeability of mammary gland cell tight junctions (TJs) and its effects on milk stability to the alcohol test. During the
M.T. Stumpf +7 more
doaj +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017 Background and Objectives: Adherence to low-sodium diet is an important aspect of self-care behaviors, which plays a role in improving the quality of life, and in reducing readmission rate, mortality, and healthcare costs. This study aimed to investigate
Sharareh Zeighami Mohammadi +6 more
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A Comprehensive Overview on Necessity and Strategies of Salt Intake Reduction in the Population [PDF]
Taṣvīr-i salāmat, 2017 Non-communicable diseases (NCDs) have become a major public health problem not only in developed countries, but also in developing countries; as cardiovascular disease is considered to be the leading cause of death in the world.
Fathollah Pourali +4 more
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What evidence for the benefits of ‘5-a-day’, a Mediterranean diet and sodium restriction on health? [PDF]
Drug and Therapeutics Bulletin, 2015 Guidelines for healthcare professionals encourage the provision of dietary advice to promote healthy eating, especially to patients at risk of chronic disease.1 Yet the evidence base for dietary interventions relies heavily on epidemiological studies, which are subject to the challenges associated with observational research.
openaire +2 more sources
ADOLESCENT BLOOD PRESSURE RESPONSE TO A SODIUM RESTRICTED DIET.
, 1983 ADOLESCENT BLOOD PRESSURE RESPONSE TO A SODIUM RESTRICTED ...
LINDA VERNER. VAN HORN (7948880)
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CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
Advanced Science, EarlyView.ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
PLoS ONE, 2017 BackgroundConsidering long-term changes in renal sodium handling and blood pressure in maternal protein-restricted (LP) offspring, we assumed that the development of LP hypertension results from abnormal dorsal root ganglia (DRG) neurokinin expression ...
Augusto H Custódio +4 more
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Key messages on sodium and sodium reduction [PDF]
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.CS323430Publication date from document properties.sodium-reduction-key-messages ...
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m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
Advanced Science, EarlyView.This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source