Results 191 to 200 of about 2,660,012 (245)

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Practical Application of Evidence-Based Dietary Therapy in Inflammatory Bowel Disease: The DELECTABLE Program. [PDF]

Nutrients
Trakman GL, Russell EE, Hamilton AL, Wilson-O'Brien A, Thompson E, Simmance N, Niewiadomski O, Kamm MA.   +7 more
europepmc   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

Polyaspartic Acid‐Calcium‐Lanthanum Complexes Induce Antibacterial Remineralization of Dentin and In‐Depth Occlusion of Dentinal Tubules

Advanced Science, EarlyView.
Polyaspartic acid‐calcium‐lanthanum (PAsp‐Ca‐La) complexes could induce antibacterial remineralization of demineralized dentin and in‐depth occlusion of dentinal tubules (DTs) with lanthanum‐doped hydroxyapatite (La‐HAp) via polyelectrolyte‐cation complexes pre‐precursor (PCCP) process, allowing the release of La3+ in response to acids generated by ...
Ling Zhu, Wei Liu, Yizhou Zhang, Zhifang Wu, Yiru Wang, Yuedan Xu, Haiyan Zheng, Hongli Zhang, Mengfei Yu, Xiaoting Jin, Zhe Wang, Zihuai Zhou, Baiping Fu   +12 more
wiley   +1 more source

Higher adherence to the EAT-Lancet reference diet is inversely associated with mortality in a UK population of cancer survivors. [PDF]

BMC Med
Karavasiloglou N, Thompson AS, Pestoni G, Suter F, Papier K, Cassidy A, Kühn T, Rohrmann S.   +7 more
europepmc   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis. [PDF]

BMC Womens Health
Naeini F, Tanha FD, Mahmoudi M, Ansar H, Hosseinzadeh-Attar MJ.   +4 more
europepmc   +1 more source

The Molecular Basis of Amino Acids Sensing

Advanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang   +3 more
wiley   +1 more source

Associations between diet quality, epigenetic aging and epigenome: Findings from two population-based Studies

Tavares JF, Liu D, Talevi V, Eichelmann F, Jannasch F, Schulze MB, Aziz NA, Nöthlings U, Breteler MM.   +8 more
europepmc   +1 more source

Effect of dietary approaches to stop hypertension diet on insulin resistance and lipid accumulation product in subjects with metabolic syndrome. [PDF]

Sci Rep
Sangouni AA, Hosseinzadeh M, Parastouei K.   +2 more
europepmc   +1 more source