Results 231 to 240 of about 23,570,638 (299)

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Harnessing of Tomato (Solanum lycopersicum) Pomace Powder on Growth Response and Haematological Indices of Sonali Chickens. [PDF]

open access: yesVet Med Sci
Habib MA   +8 more
europepmc   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

open access: yesAdvanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li   +16 more
wiley   +1 more source

The diet supplemented with raw and hydrolyzed Microchloropsis gaditana and Arthrospira platensis blend modulates intestinal microbiota and metabolomic profiles in Sparus aurata. [PDF]

open access: yesFish Physiol Biochem
Rohra-Benítez S   +7 more
europepmc   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

Larval diet-mediated morphological trait and <i>Wolbachia</i> density variation in <i>Wolbachia</i>-transinfected (<i>w</i>Mel and <i>w</i>AlbB) and <i>Wolbachia</i>-free <i>Aedes aegypti</i> mosquitoes. [PDF]

open access: yesFront Insect Sci
Revi A   +16 more
europepmc   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

open access: yesAdvanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu   +4 more
wiley   +1 more source

Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts. [PDF]

open access: yesNat Commun
Tavares JF   +8 more
europepmc   +1 more source

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