Results 61 to 70 of about 23,570,638 (299)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Diet and diabetes [PDF]

open access: yes, 2015
Provides current evidence regarding the differing diets in diabetes prevention and management once type 2 diabetes mellitus (T2DM) arises, including the role in management of complications such as = hypoglycaemia.
John Barlow   +4 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Ultrasound measurements of carotid intima-media thickness and plaque in HIV-infected patients on the Mediterranean diet [PDF]

open access: yes, 2013
Aim To evaluate the influence of food habits, specifically adherence to the Mediterranean diet, on carotid intimamedia thickness (CIMT) and the presence of plaques in HIV-infected patients taking antiretroviral therapy (ART) and non-HIV-infected ...
Brnić, Z   +17 more
core   +1 more source

Nanopore short‐read sequencing: A quick, cost‐effective and accurate method for DNA metabarcoding

open access: yesEnvironmental DNA, 2023
Dietary and predator–prey studies are more frequently relying on DNA metabarcoding methods, typically achieving results that have a better taxonomic resolution (e.g., species‐level) than previous methods.
Aimee L. van der Reis   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Mediterranean diet and the metabolic syndrome [PDF]

open access: yes, 2009
Mediterranean diet and the metabolic syndrome Background: The metabolic syndrome refers to a clustering of risk factors including abdominal obesity, hyperglycaemia, low HDL-cholesterol, hypertriglyceridaemia, and hypertension and it is a risk factor ...
Bos, M.B.
core  

A freshwater diet-derived 14C reservoir effect at the Stone Age sites in the Iron Gates gorge [PDF]

open access: yes, 2001
Human bones from single inhumation burials and artifacts made from terrestrial mammal (ungulate) bone found in direct association with the skeletons were obtained from the Stone Age site of Schela Cladovei situated just below the Iron Gates Gorge of the ...
McSweeney, Kathleen   +11 more
core   +1 more source

Field investigation‐ and dietary metabarcoding‐based screening of arthropods that prey on primary tea pests

open access: yesEcology and Evolution, 2022
Predatory natural enemies play key functional roles in biological control. Abundant predatory arthropod species have been recorded in tea plantation ecosystems.
Tingbang Yang   +4 more
doaj   +1 more source

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