Results 81 to 90 of about 717,914 (288)

Report of the Commission on Dietary Supplement Labels

, 1997
Final report of the Commission on Dietary Supplement Labels describing their activities and findings regarding the safety of dietary supplements, including sections on pertinent legislation, consumer use, labeling, and nutritional ...
Commission on Dietary Supplement Labels
core  

Dietary Antioxidants and Human Cancer [PDF]

Integrative Cancer Therapies, 2004
Epidemiological studies show that a high intake of anti-oxidant-rich foods is inversely related to cancer risk. While animal and cell cultures confirm the anticancer effects of antioxidants, intervention trials to determine their ability to reduce cancer risk have been inconclusive, although selenium and vitamin E reduced the risk of some forms of ...
openaire   +3 more sources

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

A novel criterion for the evaluation of the contrast capacity of antioxidants toward lipid peroxidation

, 2015
In order to overcome the uncertain derived from the different in vitro chemical-based assays described in literature to determine the antioxidant capacity of natural products, the oxygraphic method for the definition of a new criterion for assessing the ...
Stevanato, Roberto, Ravagnan, Giampietro, Sicari, Michela, Lucchini, Vittorio   +3 more
core  

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

You are what you eat : Within-subject increases in fruit and vegetable consumption confer beneficial skin-color changes [PDF]

, 2012
R Whitehead was funded by an ESRC Studentship.Background: Fruit and vegetable consumption and ingestion of carotenoids have been found to be associated with human skin-color (yellowness) in a recent cross-sectional study. This carotenoid-based coloration
Xiao, Dengke, Gozde Ozakinci, David I Perrett, Perrett David I., Daniel Re, Whitehead Ross D., Dengke Xiao, Re Daniel, Ross D Whitehead, Re, Daniel, Xiao Dengke, Ozakinci Gozde, Ozakinci, Gozde, Perrett, David Ian, Whitehead, Ross David   +14 more
core   +2 more sources

Dietary antioxidants for chronic periodontitis prevention and its treatment: a review on current evidences from animal and human studies

Ars Pharmaceutica, 2015
Objectives: Given the relationship between chronic periodontitis and high levels of oxidative stress, this review aims to clarify what role can played the dietary intake of different antioxidants in maintaining a healthy periodontium and in reducing ...
Alfonso Varela-López, Maurizio Battino, Pedro Bullón, José L. Quiles   +3 more
doaj  

Machine learning-based prediction of osteoporosis in prefrail and frail older adults: insights from SHAP analysis of dietary antioxidants

Critical Public Health
Osteoporosis poses significant risks in frail older adults. While oxidative stress influences bone metabolism and dietary antioxidants may provide protection, their predictive value for osteoporosis risk remains underexplored. To develop machine learning
Yuwen ShangGuan, Lin Hu, Kunpeng Wu, Young-Je Sim, Chuang Zhang, Yawei Song, Dong Li, Haobiao Liu, Zhenhao Lin, Litao Yan   +9 more
doaj   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source