Results 141 to 150 of about 90,273,184 (284)

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Faecal metabolites as a readout of habitual diet capture dietary interactions with the gut microbiome

Nature Communications
The interplay between diet and gut microbiome composition is complex. Faecal metabolites, the end products of human and microbial metabolism, provide insights into these interactions.
Robert Pope, Alessia Visconti, Xinyuan Zhang, Panayiotis Louca, Andrei-Florin Baleanu, Yu Lin, Francesco Asnicar, Kate Bermingham, Kari E. Wong, Gregory A. Michelotti, Jonathan Wolf, Nicola Segata, Sarah E. Berry, Tim D. Spector, Emily R. Leeming, Rachel Gibson, Cristina Menni, Mario Falchi   +17 more
doaj   +1 more source

Dietary approaches to stop hypertension diet and metabolic syndrome [PDF]

The Journal of Pediatrics, 2016
openaire   +2 more sources

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Association of Life's Essential 8 Score With Incident Pancreatic Cancer: A Prospective Cohort Study in Shanghai, China

Cancer Science, EarlyView.
In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi, Xing Liu, Maryam Zaid, Kexin Zhang, Biying Wang, Yingqi Deng, Minhua Tang, Yonggen Jiang, Genming Zhao   +8 more
wiley   +1 more source

Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions

Computer Graphics Forum, EarlyView.
Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh, Foroozan Daneshzand, Matteo Sotelo, Mahsa Sinaei, Fateme Rajabiyazdi   +4 more
wiley   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Type 2 diabetes remission following a comprehensive metabolic program including surgery in adults with BMI ≥50 kg/m2 versus BMI <50 kg/m2

Diabetic Medicine, EarlyView.
Abstract Aims Previous reports have suggested that higher baseline BMI (bBMI) or %excess weight loss (EWL) are independent predictors of type 2 diabetes mellitus (T2DM) remission after metabolic bariatric surgery (MBS). However, %EWL appears lower in individuals with bBMI ≥50 kg/m2 than those with lower bBMI.
Xi May Zhen, Annette Macdonald, Benjamin Woodham, Brendan Ryan, Tien‐Ming Hng, Eileene Azar, Marina Hanna, Jesmine Yap, Jeenat Paulose, Guizhi Li, Stephen M. Twigg, Golo Ahlenstiel, Jencia Wong   +12 more
wiley   +1 more source