Results 161 to 170 of about 86,851,332 (285)

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Dietary Approaches to Stop Hypertension (DASH) Diet, Incident Heart Failure and Its Associated Risk Factors in Australian Women. [PDF]

Medicina (Kaunas)
Liao LP, Marschner S, Gan GCH, Thomas L, Hodge A, Min H, Fontana L, Zaman S, Pant A.   +8 more
europepmc   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Association between the Dietary Approaches to Stop Hypertension (DASH) diet and risk of incident heart failure and heart failure-related death: a UK Biobank cohort study. [PDF]

Open Heart
Liao LP, De Paz P, Marschner S, Gan GCH, Thomas L, Fontana L, Zaman S.   +6 more
europepmc   +1 more source

Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland

Diabetic Medicine, EarlyView.
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney, Malak Hamza, Priscilla Sarkar, Harriet Morgan, Nicole Green, James Ridgeway, Victoria Alabraba, Laura Willcocks, Krupali Chandracant, Kashmala Javed, Rhys O'Callaghan, Finley Turner, Samuel Seidu, Claire L. Meek, Melanie J. Davies   +14 more
wiley   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Association between adherence to the Dietary Approaches to Stop Hypertension diet and depression and anxiety severity in the Mashhad Stroke and Heart Atherosclerotic Disorder study population. [PDF]

Public Health Nutr
Soltani S, Rahimi HR, Seifi N, Omouri-Kharashtomi M, Norouzkhani N, Ahsan M, Mohtarami M, Mohammadian Sadabad F, Sarvari N, Ferns GA, Ghayour-Mobarhan M.   +10 more
europepmc   +1 more source

Multi‐Dimensional Barriers for Work Productivity and Possible Solutions to Overcome Presenteeism in Young‐Onset Diabetes: A Mixed‐Methods Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Young‐onset non‐type 1 diabetes (YOD, age‐at‐diagnosis ≤ 40) is associated with poor physical and mental health, presenteeism and productivity loss. We examined patient‐perceived barriers to work productivity and key enablers to reduce presenteeism. Materials and Methods In this mixed‐methods study, we utilized validated questionnaires to
Kelly T. C. Wong, Jason D. C. Yin, Sunny C. S. Chan, Nga Sze Wong, Chun‐Kwan O, Yiming Dai, Yuzheng Zhang, Marques S.N. Ng, Risa Ozaki, Ronald C. W. Ma, Alice P. S. Kong, Andrea O. Y. Luk, Elaine Y.K. Chow, Juliana C. N. Chan, Juliana N. M. Lui   +14 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Research progress on Mediterranean⁃dietary approaches to stop hypertension intervention for neurodegenerative delay

Huli yanjiu
This paper reviewed the related concepts,mechanisms of action and application status of the Mediterranean⁃dietary approaches to stop hypertension intervention for neurodegenerative delay(MIND) diet,so as to provide reference for the application of the ...
JIAO Yuxiao, HE Xiaofei, MA Lulu, ZHANG Bo, ZHU Lanyu   +4 more
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