British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn +10 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys +14 more
wiley +1 more source
Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights
British Journal of Pharmacology, EarlyView.Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra +5 more
wiley +1 more source
Cancer Science, EarlyView.In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi +8 more
wiley +1 more source
Dietary approaches to stop hypertension (DASH): Results and implications [PDF]
American Journal of Hypertension, 1998 openaire +1 more source
Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review
Clinical &Experimental Allergy, EarlyView.Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng +2 more
wiley +1 more source
Mediterranean or Dietary Approaches To Stop Hypertension Diet In Lowering Hypertension In Women With Gestational Diabetes Mellitus, US National Health And Nutrition Examination Survey (NHANES), 2007-2016 [PDF]
This study aimed to address the difference in adherence to the Mediterranean and Dietary Approaches to Stop Hypertension (DASH) in lowering hypertension among women with GDM.
Carroll-Marlow, Erica
core +1 more source
Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis. [PDF]
Food Sci NutrYang B +18 more
europepmc +1 more source
Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions
Computer Graphics Forum, EarlyView.Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh +4 more
wiley +1 more source
Qualitative study of barriers and facilitators to Dietary Approaches to Stop Hypertension (DASH) on the Caribbean island of Montserrat. [PDF]
BMJ Public HealthBerners-Lee B +8 more
europepmc +1 more source