Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo+8 more
wiley +1 more source
Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies
The proper dietary calcium intake and calcium supplementation, when indicated, are important factors in the acquisition of peak bone mass during youth and in the prevention of fractures in old age.
Guilherme Alcantara Cunha Lima+7 more
doaj +1 more source
A proposed nutrient density score that includes food groups and nutrients to better align with dietary guidance. [PDF]
Current research on diets and health focuses on composite food patterns and their likely impact on health outcomes. The Dietary Guidelines for Americans (DGA) have likewise adopted a more food group-based approach.
Drewnowski, Adam+3 more
core
Calcium supplements and cancer risk : a meta-analysis of randomised controlled trials [PDF]
Peer reviewedPublisher ...
Avenell, Alison+6 more
core +1 more source
Advanced Oral Delivery Systems for Nutraceuticals
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang+4 more
wiley +1 more source
Nutritional Contributions of Nonalcoholic Beverages to the U.S. Diet: 1998-2003 [PDF]
Using data from U.S. households over the period 1998 to 2003, we examine economic and demographic factors affecting per capita daily intake of calories, calcium, caffeine, and vitamin C derived from the consumption of nonalcoholic beverages.
Capps, Oral, Jr.+2 more
core +1 more source
A profiling analysis of contributions of cigarette smoking, dietary calcium intakes, and physical activity to fragility fracture in the elderly [PDF]
Fragility fracture and bone mineral density (BMD) are influenced by common and modifiable lifestyle factors. In this study, we sought to define the contribution of lifestyle factors to fracture risk by using a profiling approach.
Center, Jacqueline R+5 more
core +1 more source
Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: evidence from discordant monozygotic twins [PDF]
Although a higher protein intake, particularly from vegetable sources, has been shown to be associated with higher bone mineral density (BMD) the relative impact of specific amino acids (AA) on BMD and risk of osteoporosis remains to be determined ...
Ammann+45 more
core +1 more source
Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li+7 more
wiley +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source