Results 171 to 180 of about 1,955,644 (376)

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

open access: yesAdvanced Science, EarlyView.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang   +10 more
wiley   +1 more source

Rice Consumption in the United States: Evidence from Food Consumption Surveys [PDF]

open access: yes
BackgroundLittle is known about rice consumption, related food intake patterns, and the nutritional contribution that rice provides in the diets of Americans.ObjectiveTo provide information about rice consumption in the United States and the diets of ...
Batres-Marquez, S. Patricia
core  

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Growth, fat metabolism and hepatic health in largemouth bass fed varying fat-level diets

open access: yesAquaculture Reports
This 60-day experiment investigated the influences of growth, fat metabolism and hepatic health of largemouth bass (Micropterus salmoides) fed varying fat diets. 225 fish (34 ± 0.04 g) were divided into three groups and fed diets with fat levels of 10 % (
Digen Qin   +8 more
doaj  

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

Dietary Fat in the Nutrition of the Growing Chick

open access: hybrid, 1958
N.T. Rand, H.M. Scott, F. A. Kummerow
openalex   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

open access: yesAdvanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun   +15 more
wiley   +1 more source

Association between dietary nutrient intake and sleep disorders in hypertensive patients: a cross-sectional study of NHANES, 2005–2020

open access: yesFrontiers in Nutrition
BackgroundDietary nutrient intake is critical for healthy sleep patterns, but studies in hypertensive patients are lacking. This study examines the connection between hypertension patients’ and their dietary nutrient intake.MethodsAdults with complete ...
Aokai Tian   +3 more
doaj   +1 more source

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