Results 221 to 230 of about 1,955,644 (376)

Dietary Fat and Androgens [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2005
openaire   +3 more sources

Adipocytes Promote Cisplatin Resistance through Secreting A1BG and Regulating NAMPT/PARP1 Axis‐Mediated DNA Repair in Osteosarcoma

open access: yesAdvanced Science, EarlyView.
The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang   +8 more
wiley   +1 more source

INFORMATIONAL EFFECTS OF NUTRIENT INTAKE DETERMINANTS ON CHOLESTEROL CONSUMPTION [PDF]

open access: yes
Nutrient information and dietary data for a sample of U.S. household meal planners are used to estimate the direct and indirect effects of various dietary determinants on cholesterol intake. Holding sociodemographic and household characteristics constant,
Blaylock, James R.   +2 more
core   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Dietary fat differentially modulates the response of bone marrow-derived macrophages to TLR4 and NOD2 agonists. [PDF]

open access: yesInnate Immun, 2023
Shehat MG   +4 more
europepmc   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang   +13 more
wiley   +1 more source

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