Results 81 to 90 of about 1,955,644 (376)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects. [PDF]

open access: yesPLoS ONE, 2013
Obesity is linked to type 2 diabetes and risk factors associated to the metabolic syndrome. Consumption of dietary fibres has been shown to have positive metabolic health effects, such as by increasing satiety, lowering blood glucose and cholesterol ...
Greta Jakobsdottir   +4 more
doaj   +1 more source

Linking livestock production to human health - creating sustainability through farming [PDF]

open access: yes, 2006
The main dietary risk factors associated with the early onset of the non-communicable diseases (cardiovascular disease (CVD) and cancer) would seem to be the over-consumption of dietary lipids and the under-consumption of dietary micronutrients. Consumer
Macrae, J C
core  

The Influence of Dietary Fat on Liver Fat Accumulation

open access: yesNutrients, 2014
Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD); however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness ...
C. Green, L. Hodson
semanticscholar   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Dietary fats and 16-year coronary heart disease mortality in a cohort of men and women in Great Britain [PDF]

open access: yes, 2002
Objective: The paper aims to investigate the relationships of dietary fats to subsequent coronary heart disease (CHD) mortality in men and women while taking account of other CHD-related behaviours.
Boniface, D.R., Tefft, M.E.
core  

Conjugated linoleic acid reduces permeability and fluidity of adipose plasma membranes from obese Zucker rats [PDF]

open access: yes, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in Biochemical and Biophysical Research Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Lopes, Paula A.   +7 more
core   +1 more source

Dietary Fat and Breast Cancer [PDF]

open access: yesJNCI: Journal of the National Cancer Institute, 1991
Good reasons exist to reduce intake of animal and partially hydrogenated fat. Existing data, however, provide little support for the hypothesis that reduction in dietary fat composition, even to 20% of energy during adulthood, will lead to a substantial reduction in breast cancer in Western cultures.
openaire   +3 more sources

Dietary fat and gestational hyperglycaemia [PDF]

open access: yesDiabetologia, 2001
The purpose of this study was to investigate the relation between life-style habits and glucose abnormalities in Caucasian women with and without conventional risk factors for gestational diabetes.A total of 126 pregnant women with gestational diabetes, 84 with impaired glucose tolerance and 294 with normal glucose tolerance, identified by sequential ...
BO, Simona   +7 more
openaire   +3 more sources

The Clinical Efficacy of Dietary Fat Restriction in Treatment of Dogs with Intestinal Lymphangiectasia

open access: yesJournal of Veterinary Internal Medicine, 2014
Background Intestinal lymphangiectasia (IL), a type of protein‐losing enteropathy (PLE), is a dilatation of lymphatic vessels within the gastrointestinal tract.
H. Okanishi   +3 more
semanticscholar   +1 more source

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