Results 111 to 120 of about 678,242 (286)
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Palm oil, its nutritional and health implications (Review)
Journal of Applied Sciences and Environmental Management, 2015 Diet for some time now in Nigeria has undergone many changes such as changes in dietary intake of fats and oils. There has been an increasing consumption of partially hydrogenated trans-vegetable oils and a decreasing intake of lauric acid-containing ...
OB Imoisi, GE Ilori, I Agho, JO Ekhator
doaj +1 more source
Dietary fats and macular degeneration
, 2006 Atherosclerosis in the blood vision and common eye diseases do not support any adverse vessels of the eye has been in non-institutionalised residents, associations between high proposed as a possible 49 years or older, living in Blue intakes of dietary ...
Victoria Flood (20120517)
core
Effects of Dietary Fats on the Fatty Acid Composition of Enamel and Dentinal Lipids of Rabbit Molars
, 1976 The fatty acid composition of enamel and dentinal lipids of the molars of rabbits fed four different fats-butter, lard, cottonseed oil, and hydrogenated cottonseed oil-was evaluated.
S.K. Das +2 more
core +1 more source
Advanced Science, EarlyView.The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo +20 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu +13 more
wiley +1 more source
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling
Cell ReportsSummary: Dietary fat composition has changed substantially during the obesity epidemic. As adipocyte hyperplasia is a major mechanism of adipose expansion, we aim to ascertain how dietary fats affect adipogenesis during obesity.
Allison Wing +15 more
doaj +1 more source
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
Advanced Science, EarlyView.The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source
Research progress on application of oil in laying poultry industry
Siliao yanjiu, 2023 Oils and fats are an important source of energy for animals and a good carrier of fat-soluble nutrients, which can participate in various life activities of the body and are widely used in animal production.
DING Yong-wang, JIN Er-hui, CHEN Wei
doaj