Results 101 to 110 of about 84,971 (289)

Palm oil, its nutritional and health implications (Review)

open access: yesJournal of Applied Sciences and Environmental Management, 2015
Diet for some time now in Nigeria has undergone many changes such as changes in dietary intake of fats and oils. There has been an increasing consumption of partially hydrogenated trans-vegetable oils and a  decreasing intake of lauric acid-containing ...
OB Imoisi, GE Ilori, I Agho, JO Ekhator
doaj   +1 more source

Nutrition Bites Video - Dietary Fats

open access: yes, 2019
Nutrition bites video titled 'Dietary fats'. Created by Monash University's Department of Nutrition, Dietetics and Food in collaboration with Monash Sport. Monash Sport filmed and edited this video. Merran Blair, BNutrDiet(Hons), APD, is featured.
Tracy McCaffrey (7419920)   +4 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

open access: yesAdvanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen   +14 more
wiley   +1 more source

Dietary fats and coronary heart disease. [PDF]

open access: yes, 1996
The prevention and treatment of coronary heart disease (CHD) necessitates vigorous dietary intervention so as 10 lower the serum cho1eslero11evel by at least 6%. Greater decreases in serum cholesterol can bring about reversal of atherosclerosis.
Temple, Norman J.
core  

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Dietary fats and macular degeneration

open access: yes, 2006
Atherosclerosis in the blood vision and common eye diseases do not support any adverse vessels of the eye has been in non-institutionalised residents, associations between high proposed as a possible 49 years or older, living in Blue intakes of dietary ...
Victoria Flood (20120517)
core  

Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study

open access: yes, 2009
Objective We aimed to describe the difference in B-vitamin intake and in plasma B-vitamin and homocysteine concentrations before and after folic acid fortification, in relation to dietary patterns. Design The Normative Aging Study (NAS) is a longitudinal
Groot, C.P.G.M., de   +5 more
core   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

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