Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis
Advanced Science, EarlyView.This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang +10 more
wiley +1 more source
Impact of Dietary Fats on Cardiovascular Disease with a Specific Focus on Omega-3 Fatty Acids. [PDF]
J Clin Med, 2022 Maggioni AP, Poli G, Mannucci PM.
europepmc +1 more source
Quality characteristics of edible linseed oil [PDF]
, 2006 In this review the quality properties of linseed oil for food uses are discussed as well as factors affecting this quality. Linseed oil has a favourable fatty acid composition with a high linolenic acid content.
Gates, Fred +3 more
core
Jornal de Pediatria: Objectives: To describe the dietary patterns of children inside and outside school and investigate their associations with sociodemographic factors and nutritional status.
Diva Aliete dos Santos Vieira +3 more
doaj +1 more source
Advanced Science, EarlyView.Researchers have identified a citrus chimera with distinctive tissue origins and carotenoid profiles. It is discovered that fruit tissues develop from all three cell layers but in different proportions. A key transcription factor, MYB107, regulates β‐cryptoxanthin production by directly activating carotenoid biosynthesis genes, explaining why some ...
Chi Zhang +8 more
wiley +1 more source
Peripheral metabolism of lipoprotein-amyloid beta as a risk factor for Alzheimer's disease: potential interactive effects of APOE genotype with dietary fats. [PDF]
Genes Nutr, 2023 D'Alonzo ZJ +5 more
europepmc +1 more source
The Influence of Dietary Fats on Serum Cholesterol Levels in Cholesterol-Fed Chicks [PDF]
, 1960 D.M. Hegsted +2 more
openalex +1 more source
The effect of supplementary grass silage and standard concentrate on milk fat fatty acid composition and iodine value when cows are fed a whole rapeseed-based concentrate at pasture [PDF]
, 2010 peer-reviewedThe use of grass silage and concentrates to supplement fresh grass intake is commonly practised in dairy systems. However, the effects of such supplementation within a dietary regime designed to produce a spreadable butter are unknown ...
Fearon, A.M. +2 more
core
Advanced Science, EarlyView.Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou +9 more
wiley +1 more source
Dietary Fats and All-cause and Breast Cancer-specific Mortality among Women with Breast Cancer: The Western New York Exposures and Breast Cancer Study. [PDF]
Cancer Epidemiol Biomarkers Prev, 2023 Meyer DS +4 more
europepmc +1 more source