Advanced Science, EarlyView.Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source
The effect of supplementary grass silage and standard concentrate on milk fat fatty acid composition and iodine value when cows are fed a whole rapeseed-based concentrate at pasture [PDF]
, 2010 peer-reviewedThe use of grass silage and concentrates to supplement fresh grass intake is commonly practised in dairy systems. However, the effects of such supplementation within a dietary regime designed to produce a spreadable butter are unknown ...
Fearon, A.M. +2 more
core
Dietary Fats and All-cause and Breast Cancer-specific Mortality among Women with Breast Cancer: The Western New York Exposures and Breast Cancer Study. [PDF]
Cancer Epidemiol Biomarkers Prev, 2023 Meyer DS +4 more
europepmc +1 more source
Advanced Science, EarlyView.This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue +13 more
wiley +1 more source
The Role of Dietary Fats in the Development and Prevention of Necrotizing Enterocolitis. [PDF]
Nutrients, 2021 Alshaikh BN +4 more
europepmc +1 more source
Advanced Science, EarlyView.In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou +13 more
wiley +1 more source
Diet quality and income in Rural and Urban China: evidence from the Health and Nutrition Survey [PDF]
The specific objective of this paper is the investigation of the link between an improvement in Chinese households’ wealth and the quality of their diet and the role played by this relationship on the overall nutrition transition process. Better economic
Capacci, Sara, Liu, Y., Mazzocchi, Mario
core +1 more source
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Advanced Science, EarlyView.Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review. [PDF]
Front Oncol, 2022 Gholamalizadeh M +12 more
europepmc +1 more source
Advanced Science, EarlyView.Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source