Results 211 to 220 of about 164,007 (344)

TRANSFORMATIONS IN THE FOOD INDUSTRY: REDUCING TRANS FAT IN THE DIET [PDF]

Food Consumption/Nutrition/Food Safety,
Reeves, Robert M.
core   +1 more source

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

Advanced Science, EarlyView.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen, Dongwei Liu, Lei Lei, Ting Liu, Shaokang Pan, Hui Wang, Yong Liu, Yingjin Qiao, Zhangsuo Liu, Qi Feng   +9 more
wiley   +1 more source

Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling

Cell Reports
Summary: Dietary fat composition has changed substantially during the obesity epidemic. As adipocyte hyperplasia is a major mechanism of adipose expansion, we aim to ascertain how dietary fats affect adipogenesis during obesity.
Allison Wing, Elise Jeffery, Christopher D. Church, Jennifer Goodell, Rocío del M. Saavedra-Peña, Moumita Saha, Brandon Holtrup, Maud Voisin, N. Sima Alavi, Mariana Floody, Zenan Wang, Thomas E. Zapadka, Michael J. Garabedian, Rohan Varshney, Michael C. Rudolph, Matthew S. Rodeheffer   +15 more
doaj  

Dietary Fats, Serum Cholesterol and Liver Cancer Risk: A Systematic Review and Meta-Analysis of Prospective Studies. [PDF]

Cancers (Basel), 2021
Zhao L, Deng C, Lin Z, Giovannucci E, Zhang X.   +4 more
europepmc   +1 more source

Influence of Strain of Chicken and Dietary Fat On Egg Production Traits [PDF]

, 1968
P.A. Kondra, Siew Choo, JERRY L. SELL
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity. [PDF]

Mol Metab
Fosch A, Pizarro DS, Zagmutt S, Reguera AC, Batallé G, Rodríguez-García M, García-Chica J, Freire-Agulleiro O, Miralpeix C, Zizzari P, Serra D, Herrero L, López M, Cota D, Rodríguez-Rodríguez R, Casals N.   +15 more
europepmc   +1 more source

Effect of Source of Carbohydrate as Influenced by Dietary Fat: Carbohydrate ratio and forced exercise in rats [PDF]

, 1968
Richard A. Ahrens, Susan S. Welsh, Yvonne L. Adams, Ruth P. Taylor, David L. Kelley   +4 more
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source