Results 141 to 150 of about 539,375 (309)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage

Journal of Lipid Research
De novo lipogenesis (DNL) has been implicated in the development and progression of liver steatosis. Hepatic DNL is strongly influenced by dietary macronutrient composition with diets high in carbohydrate increasing DNL while diets high in fat decrease ...
Lewin Small, Tuong-Vi Nguyen, Mark Larance, Darren N. Saunders, Andrew J. Hoy, Carsten Schmitz-Peiffer, Gregory J. Cooney, Amanda E. Brandon   +7 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Fighting Sarcopenia in Ageing European Adults: The Importance of the Amount and Source of Dietary Proteins. [PDF]

Nutrients, 2020
Montiel-Rojas D, Nilsson A, Santoro A, Bazzocchi A, de Groot LCPGM, Feskens EJM, Berendsen AAM, Madej D, Kaluza J, Pietruszka B, Jennings A, Fairweather-Tait S, Battista G, Capri M, Franceschi C, Kadi F.   +15 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Allergy to cow's milk proteins and lactase deficiency: a clinical dilemma in infants

Лечащий Врач
Background. When allergic to cow's milk proteins and lactase deficiency, the clinical symptoms of the gastrointestinal tract often have great similarities, so neonatologists and pediatricians often have serious difficulties in making a diagnosis. Surveys
A. F. Kiosov
doaj   +1 more source

Animal, Plant, Collagen and Blended Dietary Proteins: Effects on Musculoskeletal Outcomes. [PDF]

Nutrients, 2020
Deane CS, Bass JJ, Crossland H, Phillips BE, Atherton PJ.   +4 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Neoformed Compounds from the Maillard Reaction in Infant Formulas: A New Risk Factor for Allergy?

European Medical Journal Allergy & Immunology, 2017
Food allergies, which are T helper cell Type 2 aberrant responses of the immune system to food proteins, are increasing. Environmental factors, including food contaminants, are often mentioned to explain this increase.
Indoumady Baskara, Céline Niquet-Leridon, Pauline M. Anton, Carine Delayre-Orthez   +3 more
doaj