Results 151 to 160 of about 539,375 (309)
Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease
Advanced Materials, EarlyView.The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang +7 more
wiley +1 more source
Difficulties encountered when treating coeliac disease : from molecule to miracle cure? [PDF]
, 2007 Dietary treatment of coeliac disease should be based on a sound theoretical knowledge of the different immunogenicities of various cereal grains, an appreciation of the limitations of the current Codex Alimentarius recommendations and an understanding of
Pullicino, Edgar
core
Advanced Materials, EarlyView.A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Novel Dietary Proteins Selectively Affect Intestinal Health In Vitro after Clostridium difficile-Secreted Toxin A Exposure. [PDF]
Nutrients, 2020 Jochems PGM +7 more
europepmc +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
Advanced Materials, EarlyView.This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
The potential role of dietary polyphenols in Parkinson’s disease [PDF]
, 2011 Cumulative evidence now suggests that the abnormal aggregation of the neuronal protein alpha-synuclein is critically involved in the pathogenesis of synucleinopathies, of which Parkinson’s disease (PD) is the most prevalent. Development of neuropathology
Caruana, Mario, Vassallo, Neville
core
Advanced Robotics Research, EarlyView.To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang +9 more
wiley +1 more source
Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins. [PDF]
PLoS One, 2020 Oparija-Rogenmozere L +4 more
europepmc +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Advanced Science, EarlyView.In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source