Results 291 to 300 of about 541,679 (339)

Mitofusin 2 is required for preventing deoxynivalenol-induced porcine intestinal epithelial cell damage. [PDF]

J Anim Sci Biotechnol
Xiao K, Zhang M, Lv Q, Huang F, Xu Q, Guo J, Zhao J, Zhu H, Chen S, Liu Y.   +9 more
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice. [PDF]

Int J Food Sci
Lin SH, Soetanto CG, Chiu WC, Cross TL, Kao NJ, Wu YR, Lin CI, Jha P.   +7 more
europepmc   +1 more source

Plasma Proteomic Profile of Dietary Potassium and Incident CKD. [PDF]

Clin J Am Soc Nephrol
Yang J, Bernard L, Chen J, Sullivan VK, Yu B, Rhee EP, Welling PA, Rebholz CM.   +7 more
europepmc   +1 more source

Dietary protein from different sources escapes host digestion and is differentially modified by gut microbiota.

Food Funct
Awan A, Bartlett A, Blakeley-Ruiz JA, Richie T, Theriot CM, Kleiner M.   +5 more
europepmc   +1 more source

Assessment of genetically modified maize DP202216 × NK603 × DAS-40278-9 (application GMFF-2022-6232). [PDF]

EFSA J
EFSA Panel on Genetically Modified Organisms (GMO), Casacuberta J, Barro F, Braeuning A, de Maagd R, Epstein MM, Frenzel T, Gallois JL, Koning F, Messéan A, Moreno FJ, Nogué F, Savoini G, Schulman AH, Tebbe C, Veromann E, Ardizzone M, De Sanctis G, Dumont AF, Ferrari A, Gennaro A, Ruiz JÁG, Goumperis T, Jacchia S, Kagkli DM, Lenzi P, Camargo AM, Neri FM, Piffanelli P, Raffaello T.   +29 more
europepmc   +1 more source

Effects of Functional Foods and Dietary Bioactives on Human Health. [PDF]

Molecules
Zhou S, Yuan L, Hu X.
europepmc   +1 more source

A Review of Nutritional Regulation of Intestinal Butyrate Synthesis: Interactions Between Dietary Polysaccharides and Proteins. [PDF]

Foods
Yuan M, Gao K, Peng K, Bi S, Cui X, Liu Y.   +5 more
europepmc   +1 more source

Similar effects between animal-based and plant-based protein blend as complementary dietary protein on muscle adaptations to resistance training: findings from a randomized clinical trial. [PDF]

J Int Soc Sports Nutr
Santini MH, Erwig Leitão A, Mazzolani BC, Smaira FI, de Souza MSC, Santamaria A, Gualano B, Roschel H.   +7 more
europepmc   +1 more source