Results 51 to 60 of about 2,200,519 (246)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The nature of the dietary protein impacts the tissue-to-diet 15N discrimination factors in laboratory rats. [PDF]

open access: yesPLoS ONE, 2011
Due to the existence of isotope effects on some metabolic pathways of amino acid and protein metabolism, animal tissues are (15)N-enriched relative to their dietary nitrogen sources and this (15)N enrichment varies among different tissues and metabolic ...
Nathalie Poupin   +5 more
doaj   +1 more source

The effect of the addition of soluble fibers (polydextrose, corn, pea) on the color, texture, structural features and protein digestibility of semolina pasta

open access: yesApplied Food Research, 2022
Wheat durum pasta was added with dietary fiber from green pea, corn or polydextrose at levels of 6, 12 and 18 g/100 g. Texture analysis showed that the dietary fiber produced cooked pasta with increased hardness, reduced elasticity and cohesiveness, the ...
M.E. Rodriguez-Huezo   +4 more
doaj   +1 more source

Dietary protein and bone health [PDF]

open access: yesProceedings of the Nutrition Society, 2003
The effects of dietary protein on bone health are paradoxical and need to be considered in context of the age, health status and usual diet of the population. Over the last 80 years numerous studies have demonstrated that a high protein intake increases urinary Ca excretion and that on average 1 mg Ca is lost in urine for every 1 g rise in dietary ...
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Dietary Protein and Physical Exercise for the Treatment of Sarcopenia

open access: yesClinics and Practice
Sarcopenia is a multifactorial age-related disorder that causes a decrease in muscle mass, strength, and function, leading to alteration of movement, risk of falls, and hospitalization.
Rosarita Nasso   +4 more
doaj   +1 more source

Dietary Requirements for Proteins and Amino Acids in Human Nutrition

open access: yes, 2019
Background: An optimal dietary Amino Acid (AA) intake is necessary for the growth of body proteins. A new method for protein quality evaluation called Digestible Indispensable AA Score (DIAAS) was established.
Peter Patráš   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Food Neophobia and Animal Protein Intake in Children Aged 3-5 Years

open access: yesDiversity
Food neophobia, defined as the avoidance of unfamiliar or familiar foods due to fear and negative perceptions, can significantly influence children’s dietary variety and nutritional adequacy. Previous studies have highlighted inconsistent findings on its
Novia Tri Khoirunnisa   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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