Results 51 to 60 of about 2,340,893 (275)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Dietary fatty acids affecting hepatic metabolism and atherosclerosis – mechanisms unravelled using a proteomics approach

open access: yesGrasas y Aceites, 2009
Dietary fatty acids play an important role in the aetiology of coronary heart disease. The effects of dietary fatty acids on lipoprotein metabolism are well described, but additional or alternative mechanisms relating to potential influence on coronary ...
Guillermo Rodríguez Gutiérrez   +1 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol

open access: yesInsects, 2020
Phytosterols are important micronutrients that are precursors of important molting hormones and help maintain cellular membrane integrity in insects including bees.
Priyadarshini Chakrabarti   +1 more
doaj   +1 more source

Subchronic dietary exposure of rats to cadmium alters the metabolism of metals essential to bone health [PDF]

open access: yes, 2004
Cadmium (Cd) was recently identified as a risk factor for osteoporosis. Skeletal damage may be the critical effect of low-level long-term exposure to Cd in the general population exposed via food, but the mechanisms behind this are not clearly understood.
M Kolf-Clauw   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Proteins, Pathologies and Politics : Dietary Innovation and Disease from the Nineteenth Century

open access: yes, 2018
Proteins, Pathologies and Politics presents an international and historical approach to dietary change and health, contrasting current concerns with how issues such as diabetes, cancer, vitamins, sugar and fat, and food allergies were perceived in the ...

core   +2 more sources

The nature of the dietary protein impacts the tissue-to-diet 15N discrimination factors in laboratory rats. [PDF]

open access: yesPLoS ONE, 2011
Due to the existence of isotope effects on some metabolic pathways of amino acid and protein metabolism, animal tissues are (15)N-enriched relative to their dietary nitrogen sources and this (15)N enrichment varies among different tissues and metabolic ...
Nathalie Poupin   +5 more
doaj   +1 more source

The effect of the addition of soluble fibers (polydextrose, corn, pea) on the color, texture, structural features and protein digestibility of semolina pasta

open access: yesApplied Food Research, 2022
Wheat durum pasta was added with dietary fiber from green pea, corn or polydextrose at levels of 6, 12 and 18 g/100 g. Texture analysis showed that the dietary fiber produced cooked pasta with increased hardness, reduced elasticity and cohesiveness, the ...
M.E. Rodriguez-Huezo   +4 more
doaj   +1 more source

Fruit, vegetable and dietary carotenoid intakes explain variation in skin-color in young caucasian women : a cross-sectional study [PDF]

open access: yes, 2015
This work was supported by a scholarship top-up grant from HMRI. Kristine Pezdirc is supported by an Australian Postgraduate Awards scholarship. Melinda Hutchesson is supported by a Postdoctoral Fellowship (100177) from the National Heart Foundation of ...
Hutchesson, Melinda J.   +13 more
core   +1 more source

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