Results 41 to 50 of about 2,200,519 (246)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A prospective double-blinded study evaluating threshold doses of dietary allergens that trigger adverse food reactions in dogs, and time to flare after exposure

Frontiers in Veterinary Science
IntroductionAdverse food reactions (AFR) are a common cause of chronic pruritus in dogs and often present as atopic dermatitis. However, the threshold dose of dietary protein required to trigger clinical signs of AFR, as well as the time to onset of ...
Laura Udraite Vovk, Laura Widorn, Georg Lehner, Ralf S. Mueller   +3 more
doaj   +1 more source

Characterization of the proteome of cytoplasmic lipid droplets in mouse enterocytes after a dietary fat challenge. [PDF]

PLoS ONE, 2015
Dietary fat absorption by the small intestine is a multistep process that regulates the uptake and delivery of essential nutrients and energy. One step of this process is the temporary storage of dietary fat in cytoplasmic lipid droplets (CLDs).
Theresa D'Aquila, Devika Sirohi, Jeffrey M Grabowski, Victoria E Hedrick, Lake N Paul, Andrew S Greenberg, Richard J Kuhn, Kimberly K Buhman   +7 more
doaj   +1 more source

Experimental atherosclerosis in rabbits on diets with milk fat and different proteins [PDF]

, 1975
In this thesis the literature about the pathogenesis of atherosclerosis has been reviewed. The various risk indicators for atherosclerosis are discussed and related to the theory about atherogenesis. A review of the influence of milk fat constituents and
Hermus, R.J.J.
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery

Journal of Cachexia, Sarcopenia and Muscle
Background Metabolic and bariatric surgery (MBS) is a proven treatment for obesity. Yet weight loss is accompanied by loss of muscle which may predispose to sarcopenia.
Gabriël Eksteen, Tim Vanuytsel, Roman Vangoitsenhoven, Ann Mertens, Matthias Lannoo, Ellen De Leus, Bart Van der Schueren, Christophe Matthys   +7 more
doaj   +1 more source

Dietary fatty acids affecting hepatic metabolism and atherosclerosis – mechanisms unravelled using a proteomics approach

Grasas y Aceites, 2009
Dietary fatty acids play an important role in the aetiology of coronary heart disease. The effects of dietary fatty acids on lipoprotein metabolism are well described, but additional or alternative mechanisms relating to potential influence on coronary ...
Guillermo Rodríguez Gutiérrez, Baukje de Roos   +1 more
doaj   +1 more source

Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol

Insects, 2020
Phytosterols are important micronutrients that are precursors of important molting hormones and help maintain cellular membrane integrity in insects including bees.
Priyadarshini Chakrabarti, Ramesh R. Sagili   +1 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Dietary Protein and Blood Pressure: A Systematic Review [PDF]

, 2010
Background - Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP.
Wieke Altorf-van der Kuil, Bakker, Stephan J. L., Navis, G., Johanna M Geleijnse, Geleijnse, J.M., Geleijnse Johanna M., Bakker Stephan J. L., van't Veer, Pieter, Bakker, Stephan J. L.; id_orcid, Marleen A van Baak, Geleijnse, Johanna M., Mariëlle F Engberink, van Baak, M.A., Mariëlle F. Engberink, Engberink, Marielle F., Stephan J L Bakker, Altorf-van der Kuil, Wieke, van Baak Marleen A., Pieter van 't Veer, Brink, Elizabeth J., Wieke Altorf – van der Kuil, Bakker, S.J., van Baak, Marleen A., Johanna M. Geleijnse, Brink Elizabeth J., Veer, P., van 't, Engberink Mariëlle F., Brink, E.J., van 't Veer Pieter, Gerjan Navis, van 't Veer, P., Marleen A. van Baak, Navis, Gerjan, Elizabeth J. Brink, Engberink, M.F., Stephan J. L. Bakker, van der Kuil, W., Navis Gerjan, Altorf-van der Kuil, W., Baak, M.A., van, Elizabeth J Brink, Altorf – van der Kuil Wieke   +41 more
core   +1 more source