Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Arthritis Care &Research, EarlyView.Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source
Associations of circulating insulin-like growth factor-I with intake of dietary proteins and other macronutrients. [PDF]
Clin Nutr, 2021 Watling CZ +10 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
Advanced Functional Materials, EarlyView.A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Food FrontiersColorectal cancer (CRC) is a common malignant tumor of the digestive tract in China; its incidence rates and mortality rates have been on the rise in recent years, ranking third in terms of incidence and second in mortality. Rational dietary intervention
Duo Feng +6 more
doaj +1 more source
Chemically Fueled Systems Chemistry Across Length Scales
Advanced Functional Materials, EarlyView.Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/functions like spatio‐temporal catalysis, oscillations, optical properties, and perform work.
Brigitte A. K. Kriebisch, Job Boekhoven
wiley +1 more source
Journal of Nutritional SciencePrevious investigations on protein associations with diet quality and obesity still have inconclusive findings, possibly due to how protein intake was expressed.
Hesti Retno Budi Arini +3 more
doaj +1 more source
Are Dietary Proteins the Key to Successful Body Weight Management? A Systematic Review and Meta-Analysis of Studies Assessing Body Weight Outcomes after Interventions with Increased Dietary Protein. [PDF]
Nutrients, 2021 Hansen TT, Astrup A, Sjödin A.
europepmc +1 more source
Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy
Advanced Healthcare Materials, EarlyView.This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato +8 more
wiley +1 more source
Effects of Dietary Patterns, Weight Loss Diets, and Dietary Components on Serum Adiponectin Levels
مجله دانشکده پزشکی اصفهان, 2012 Background: Adiponectin, an adipocytokine secreted by adipose tissue, is negatively related with body fat mass. It plays an important role in insulin sensitivity and improvement of lipid profile, cardiovascular diseases, and inflammation.
Vajihe Izadi, Leila Azadbakht
doaj