Results 41 to 50 of about 2,412,887 (298)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Dietary assessment methods for micronutrient intake in elderly people: a systematic review [PDF]

, 2009
The European micronutrient recommendations aligned (EURRECA) Network of Excellence seeks to establish clear guidelines for assessing the validity of reported micronutrient intakes among vulnerable population groups.
Jorge Doreste-Alonso, Serra-Majem, L., Vries, Jeanne de, Lluís Serra-Majem, de Vries, J.H.M., Groot, C.P.G.M., de, Almudena Sánchez-Villegas, Groot, Lisette de, Vries, J.H.M., de, Ortiz-Andrellucchi, A., Sanzech-Villegas, A., de Groot, C.P.G.M., Jeanne de Vries, Ortiz-Andrellucchi, Adriana, Doreste-Alonso, Jorge, Doreste-Alonso, J., Adriana Ortiz-Andrellucchi, Serra-Majem, Lluís, Lisette de Groot, Sánchez-Villegas, Almudena   +19 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

Arthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source

Development of the Ajinomoto Group Nutrient Profiling System for Japanese Meals

Frontiers in Nutrition
IntroductionNutrient profiling (NP) is a method used to classify or score foods based on their nutritional content and impact on human health. The Ajinomoto Group Nutrient Profiling System (ANPS) was previously developed to evaluate the nutritional value
Hiroko Jinzu, Keishiro Arima, Hiroaki Kobayashi, Shunji Sakai, Sachi Nii, Yuki Nakayama, Yuki Okabe, Chie Furuta   +7 more
doaj   +1 more source

Sociodemographic and Lifestyle Determinants of Adherence to Current Dietary Recommendations and Diet Quality in Middle-Aged Spanish Premenopausal Women

Frontiers in Nutrition, 2022
BackgroundA healthy diet when approaching menopause could prevent some of the symptoms associated with the climacteric. Few studies examine adherence to current healthy dietary recommendations in middle-aged premenopausal women.
Marina Alonso-Cabezas, Marina Pollán, Marina Pollán, Isabel Alonso-Ledesma, Nerea Fernández de Larrea-Baz, Nerea Fernández de Larrea-Baz, Pilar Lucas, Ángeles Sierra, Ángeles Sierra, Adela Castelló, Adela Castelló, Adela Castelló, Marina Nieves Pino, Beatriz Pérez-Gómez, Beatriz Pérez-Gómez, Mercedes Martínez-Cortés, Virginia Lope, Virginia Lope, Emma Ruiz-Moreno, Emma Ruiz-Moreno   +19 more
doaj   +1 more source

Dietary iron intake during early pregnancy and birth outcomes in a cohort of British women [PDF]

, 2011
Background: Iron deficiency during pregnancy is associated with adverse birth outcomes, particularly, if present during early gestation. Iron supplements are widely recommended during pregnancy, but evidence of their benefit in relation to infant ...
Greenwood, Darren C, Godfrey, KM, Simpson, NAB, J. E. Cade, McArdle, Harry J, D. C. Greenwood, Greenwood, Darren C., Alwan, NA, Simpson, Nigel A B, Greenwood, DC, Godfrey, Keith M, H. J. McArdle, McArdle, Harry J., Simpson, Nigel A.B., McArdle, HJ, K. M. Godfrey, Alwan, Nisreen A, Cade, Janet E, Cade, Janet E., Cade, JE, N. A. Alwan, N. A. B. Simpson, Alwan, Nisreen A., Godfrey, Keith M.   +23 more
core   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

A comparison of development methods used to define portion sizes in food-based dietary guidelines around the world

Frontiers in Nutrition
IntroductionFood-based dietary guidelines (FBDGs) are essential public health tools for delivering dietary recommendations, and generally include guidance on portion sizes.
Fanny Salesse, Fanny Salesse, Alison L. Eldridge, Tsz Ning Mak, Eileen R. Gibney, Eileen R. Gibney   +5 more
doaj   +1 more source