Results 171 to 180 of about 2,098,851 (295)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Prevalence and Associated Factors of Excessive Dietary Supplement Use Among Japanese Adults: Cross-Sectional Study.

Interact J Med Res
Sugimoto M, Asakura K, Shinozaki N, Murakami K.   +3 more
europepmc   +1 more source

Ethical Failures in the Digital Age: Social Media's Role in Vietnam's Herbal and Dietary Supplement Crisis. [PDF]

Hosp Pharm
Chau HTB, Vinh DP, Long TT, Thu TTA, Tham TN, Do VM, Huy NT.   +6 more
europepmc   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Patterns, motivations, and determinants of dietary supplement use among physically active adults in Eastern Saudi Arabia: a cross-sectional survey. [PDF]

Front Public Health
Alhumaid MM, Alobaid MA, Said MA.
europepmc   +1 more source

Hepatotoxicity associated with the dietary supplement OxyELITE Pro™ - Hawaii, 2013.

Drug Testing and Analysis, 2016
D. Johnston, A. Chang, M. Viray, K. Chatham-Stephens, Hua He, E. Taylor, L. Wong, J. Schier, Colleen A Martin, D. Fabricant, Monique Salter, Lauren S. Lewis, Sarah Y. Park   +12 more
semanticscholar   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Effect on consumers' sustainable purchase intention of dietary supplement purine labeling. [PDF]

Front Nutr
Yang D, Gui G, Yao Y, Ke X.
europepmc   +1 more source

Iodine in food- and dietary supplement-composition databases.

American Journal of Clinical Nutrition, 2016
P. Pehrsson, K. Patterson, J. Spungen, M. Wirtz, K. Andrews, J. Dwyer, C. Swanson   +6 more
semanticscholar   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source