Results 181 to 190 of about 1,930,737 (383)
Advanced Science, EarlyView.This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen +9 more
wiley +1 more source
Journal of Medicinal Plants, 2020 Background: Senile dementia is the most common kind of dementia with considerable social and economic costs. Since the nature of disease is multi-pathological, current treatments cannot cover all aspects of the disease.
Mohammad Mahdi Ahmadian-Attari +3 more
doaj
Cadmium-Induced Fetal Growth Retardation in Mice and the Effects of Dietary Supplements of Zinc, Copper, Iron and Selenium [PDF]
, 1979 William S. Webster
openalex +1 more source
Advanced Science, EarlyView.An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang +10 more
wiley +1 more source
Dietary Supplements: business and utility
European Journal of Biomedical and Life Sciences, 2016 The use of dietary supplements is rapidly increasing but, are we using them in a proper way? Are they really useful for us?
openaire +3 more sources
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Advanced Science, EarlyView.Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji +12 more
wiley +1 more source
Advanced Science, EarlyView.The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen +8 more
wiley +1 more source
The Effect of Prolonged Supplementation of Dietary Zinc on Weight Gain, Tissue Storage of Zinc and some Serum Variables in Fattening Pigs [PDF]
, 1976 Κjell Martinsson, L. Ekman
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Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source