Results 261 to 270 of about 1,930,737 (383)

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

Advanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan, Dongxiao Cui, Jiajian Guo, Xiaojing Ma, Jiaming Wang, Linyue Guo, Tianyu Li, Mingrui Yang, Guangrui Huang, Anlong Xu, Wenfu Ma   +10 more
wiley   +1 more source

Open-label pilot study using hydroxytyrosol as dietary supplements in patients with mitochondrial diseases. [PDF]

Orphanet J Rare Dis
Wong TS, Man E, Wong ICK, Li SX, Zhi H, Yeung KMC, Yip KY, Kwong AKY, Belaramani KM, Wong SN, Kwok AMK, Mak M, Chan TCH, Lau PY, Kan YLE, Wong KC, Poon F, Kwok V, Li CYD, Lau P, Lam SM, Chu V, Chan CFG, Fung CW.   +23 more
europepmc   +1 more source

Partial Alleviation of Phenylalanine Toxicity in the Chick by Supplemental Dietary Tryptophan

, 1983
Robert G. Elkin, J.C. Rogler
openalex   +1 more source

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

Advanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing, Ruohong Wang, Tianzhang Kou, Wenbin Liu, Zheng‐Jiang Zhu   +4 more
wiley   +1 more source

Phytosterol-Enriched Dietary Supplements for Lowering Plasma LDL-Cholesterol: Yes or No? [PDF]

Nutrients
Stellaard F, Lütjohann D.
europepmc   +1 more source

Effects of Dietary Calcium, Vitamin D3, and Corn Supplementation on Growth Performance and Mineral Metabolism in Young Goats Fed Whole Milk Diets

, 1986
Tina Hines, N.L. Jacobson, Donald C. Beitz, E. Travis Littledike   +3 more
openalex   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

Strengthening Dietary Supplement Research: An Expanded Priority for the NIH Office of Dietary Supplements. [PDF]

Am J Clin Nutr
Pasiakos SM, Kuszak AJ.
europepmc   +1 more source

Plasma, platelet, and aorta fatty acids composition in response to dietary n-6 and n-3 fats supplementation in a rat model of non-insulin-dependent diabetes.

, 1988
Ryutaro Takahashi, N. M. Fisher, David F. Horrobin   +2 more
openalex   +2 more sources

PlantGPT: An Arabidopsis‐Based Intelligent Agent that Answers Questions about Plant Functional Genomics

Advanced Science, EarlyView.
PlantGPT integrates 60 000+ plant research articles with Arabidopsis phenotype‐gene data through retrieval‐augmented generation and fine‐tuning of Llama3‐8B. This open‐source, specialized AI system outperforms general large language models in plant gene‐phenotype relationships, establishing a new paradigm for functional genomics research and molecular ...
Ruixiang Zhang, Yu Wang, Weiyang Yang, Jun Wen, Weizhi Liu, Shipeng Zhi, Guangzhou Li, Nan Chai, Jiaqi Huang, Yongyao Xie, Xianrong Xie, Letian Chen, Miao Gu, Yao‐Guang Liu, Qinlong Zhu   +14 more
wiley   +1 more source