Results 51 to 60 of about 9,178 (246)

Chiral benzimidazoles as hydrogen bonding organocatalysts [PDF]

open access: yes, 2015
Several bifunctional organocatalysts bearing the benzimidazole unit have been designed in order to act as bifunctional systems by hydrogen bonding. Chiral 2-aminobenzimidazoles are conformational rigid guanidines able to catalyze enantioselectively ...
Nájera, Carmen, Yus, Miguel
core   +2 more sources

Addition-substitution reactions of 2-thio-3-chloroacrylamides with carbon, nitrogen, oxygen, sulfur and selenium nucleophiles [PDF]

open access: yes, 2011
Synthetically versatile conjugate addition of a range of carbon, nitrogen, oxygen, sulfur and selenium nucleophiles to the highly functionalised 2-thio-3-chloroacrylamides is described.
Chopra, Jay   +7 more
core   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

Volatile Profile Characterization of Croatian Commercial Sparkling Wines

open access: yesMolecules, 2020
Commercial sparkling wine production represents a relatively low but important part of the Croatian wine production, especially in the Zagreb county.
Ana-Marija Jagatić Korenika   +3 more
doaj   +1 more source

Synthesis of 3α,12α-dihydroxy-23a, 23b-dihomo-5β-cholan-24-oic acid [PDF]

open access: yesJournal of the Serbian Chemical Society, 2004
A novel multi-step synthesis of 3α,12α-dihydroxy-23a,23b-dihomo-5β-cholan 24-oic acid (23a,23b-dihomodeoxycholic acid) (5) has been achieved from methyl 3α,12α-dihydroxy-5β-cholanoate (1).
Ćirin-Novta Vera S.   +3 more
doaj   +1 more source

The degradation of L-lysine in guinea pig liver homogenate: formation of alpha-aminoadipic acid [PDF]

open access: yes, 1948
A summary of the little that is known of the metabolism of lysine in animals is as follows: it is indispensable in the diet, its α-amino group does not participate in reversible transamination reaction in vivo (2), neither the L nor D form is attacked by
Borsook, Henry   +4 more
core   +1 more source

Quantifying the Electrophilicity of 9(10H)‐Phenanthrenone‐ and 1‐Acenaphthenone‐Derived α, β‐Unsaturated Ketones

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 2, February 2026.
The electrophilicities (Mayr E) of the α, β‐unsaturated ketones A and B were determined by kinetic studies of their reactions with carbanions (reference nucleophiles) in DMSO at 20°C. The different reactivities of A and B were rationalized by DFT calculations.
Christoph Gross   +5 more
wiley   +1 more source

The synthesis and biodistribution of 3‐(4′‐[ 125 I]‐iodophenyl)‐4‐aminobutyric acid, a radioiodinated analogue of baclofen [PDF]

open access: yes, 1990
Baclofen has been found to bind to receptors in the central nervous system that are specific for γ‐aminobutyric acid (GABA), a well known inhibitory neurotransmitter. This paper describes the synthesis of a radioiodinated analog of baclofen as part of an
Allen   +7 more
core   +1 more source

Hoveyda–Grubbs 1st and 2nd Generation Precatalysts Modified in the Alkoxybenzylidene Part With Long (Fluorous) Chains: Catalytic Activity and Stability

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
We synthesized a series of light to heavy fluorous Hoveyda–Grubbs precatalyst analogs modified in the alkoxybenzylidene part in positions 2 and 5 by long (fluorinated) ponytails and tested their activity in ring‐closing metathesis. The substitution mostly resulted in accelerated reaction but the precatalyst stability often decreased.
Pavlína Dundálková   +4 more
wiley   +1 more source

Well-defined silica-supported olefin metathesis catalysts [PDF]

open access: yes, 2009
Two triethoxysilyl-functionalized N-heterocyclic carbene ligands have been synthesized and used to prepare the corresponding second-generation ruthenium olefin metathesis catalysts.
Allen, Daryl P.   +2 more
core   +1 more source

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