Results 81 to 90 of about 9,178 (246)
Cycloaddition and Annulation Reactions with Donor‐Acceptor Cyclobutanes
Helvetica Chimica Acta, Volume 108, Issue 11, November 2025.Reviewing the rise of donor‐acceptor cyclobutanes in (4 + 2) annulations, from Lewis/Brønsted acid to electrocatalysis, enabling stereoselective access to complex heterocycles and natural products. Abstract Donor‐acceptor (DA) cyclobutanes are emerging as valuable synthetic intermediates due to their ring strain and polarized C─C bonds, which allow for
Emma G. L. Robert, Jerome Waser
wiley +1 more source
Malonylation/Decarbalkoxylation of Furan Derivatives as Key Steps for the Preparation of Nonactic Acid Derivatives. Part I [1] [PDF]
, 2018 Summary.: A malonylation/decarbalkoxylation sequence from 2-substituted furans was investigated in view of developing a scalable synthesis of hydrophobic nonactic acid ...
Bobal, Pavel +5 more
core +1 more source
ChemistryOpen, Volume 14, Issue 11, November 2025.KOtBu‐promoted facile and practical synthesis of various substituted piperidine‐2,6‐diones between methyl acetates and acrylamides via a Michael addition/intramolecular imidation cascade sequence has been disclosed. And reaction scale‐up, further transformation of representative products, and preparation of bioactive molecules (e. g.
Yue‐Hua Liu +7 more
wiley +1 more source
Synthesis and antimicrobial evaluation of 3-hydrazino-naphthoquinones as analogs of lapachol
Journal of the Brazilian Chemical Society, 2001 Several 1,4-naphthoquinone derivatives having a hydrazino side chain were synthesized from 3-diazo-naphthalene-1,2,4-trione and tested as potential antimicrobial agents.
Oliveira Claudia G. T. +6 more
doaj
Three-Component Coupling Reactions of Arynes for the Synthesis of Benzofurans and Coumarins
Molecules, 2014 The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles.
Eito Yoshioka +2 more
doaj +1 more source
Enantioselective isothiourea catalysed Michael-Michael-lactonisation cascade; synthesis of δ-lactones and 1,2,3,4-substituted cyclopentanes [PDF]
, 2017 The authors thank the EPSRC (ERTR – grant code EP/J500549/1; ABF - grant code EP/J018139/1), the Spanish government for a FPU Fellowship and the University of Seville (V Plan Propio de Investigación) for financial support (PER).
Elías-Rodríguez, Pilar +3 more
core +1 more source
Carbon Dots as Nano‐Photocatalysts: A Green Tool for Indole and Heteroarenes Alkylation
Chemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.A nano‐photocatalytic method for the functionalization of indoles and heteroarenes is reported. The reaction is promoted by the photocatalytic activity of carbon nanodots, which was thoroughly investigated by mechanistic studies to determine the reaction mechanism.
Jules Sargueil +10 more
wiley +1 more source
Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs
European Journal of Organic Chemistry, Volume 28, Issue 38, October 15, 2025.Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar +7 more
wiley +1 more source
Heliyon, 2020 The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (a-e) in four steps starting from substituted salicylaldehyde 1 (a-e), and diethyl malonate 2.
Vagish Channa Basappa +5 more
doaj +1 more source