Results 81 to 90 of about 8,721 (248)
Chemistry – A European Journal, Volume 31, Issue 35, June 23, 2025.The insertion of a fluorescent coumarin unit by using a lysine‐based linker on deferoxamine leads to a chelating agent (DFOKC), whose Cu(II) and Zr(IV) complexes can be used for both optical imaging and positron emission tomography. DFOKC shows increased binding ability for Cu(II) and Zr(II) and improved tumor cell internalization via pinocytosis ...
Yschtar Tecla Simonini Steiner +8 more
wiley +1 more source
Latent olefin metathesis catalysts [PDF]
, 2009 Olefin metathesis is a versatile synthetic tool for the redistribution of alkylidene fragments at carbon-carbon double bonds. This field, and more specifically the development of task-specific, latent catalysts, attracts emerging industrial and academic ...
Drozdzak, Renata +4 more
core +2 more sources
Three-Component Coupling Reactions of Arynes for the Synthesis of Benzofurans and Coumarins
Molecules, 2014 The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles.
Eito Yoshioka +2 more
doaj +1 more source
Malonylation/Decarbalkoxylation of Furan Derivatives as Key Steps for the Preparation of Nonactic Acid Derivatives. Part I [1] [PDF]
, 2018 Summary.: A malonylation/decarbalkoxylation sequence from 2-substituted furans was investigated in view of developing a scalable synthesis of hydrophobic nonactic acid ...
Bobal, Pavel +5 more
core +1 more source
An optimised Bcl‐3 inhibitor for melanoma treatment
British Journal of Pharmacology, Volume 182, Issue 11, Page 2426-2446, June 2025.Abstract Background and Purpose Malignant melanoma is the most lethal form of skin cancer, characterised by a poor survival rate. One of the key factors driving the aggressive growth of melanoma cells is the elevated expression of the proto‐oncogene Bcl‐3. This study aims to optimise, evaluate and characterise a second‐generation Bcl‐3 inhibitor, using
Karunakar Saamarthy +8 more
wiley +1 more source
Synthesis and antimicrobial evaluation of 3-hydrazino-naphthoquinones as analogs of lapachol
Journal of the Brazilian Chemical Society, 2001 Several 1,4-naphthoquinone derivatives having a hydrazino side chain were synthesized from 3-diazo-naphthalene-1,2,4-trione and tested as potential antimicrobial agents.
Oliveira Claudia G. T. +6 more
doaj
Crystal structure of diethyl 2-[(2-sulfanylquinolin-3-yl)methylidene]malonate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C17H17N O4S, the quinoline ring system is nearly planar, with a maximum deviation of 0.0496 (16) Å. A weak intramolecular C—H...O interaction is observed.
Rihanabanu +4 more
doaj +1 more source
Enantioselective isothiourea catalysed Michael-Michael-lactonisation cascade; synthesis of δ-lactones and 1,2,3,4-substituted cyclopentanes [PDF]
, 2017 The authors thank the EPSRC (ERTR – grant code EP/J500549/1; ABF - grant code EP/J018139/1), the Spanish government for a FPU Fellowship and the University of Seville (V Plan Propio de Investigación) for financial support (PER).
Elías-Rodríguez, Pilar +3 more
core +1 more source
Heliyon, 2020 The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (a-e) in four steps starting from substituted salicylaldehyde 1 (a-e), and diethyl malonate 2.
Vagish Channa Basappa +5 more
doaj +1 more source