Results 201 to 210 of about 328,615 (242)
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Onchocerciasis treated with diethylcarbamazine
British Journal of Dermatology, 1977One hundred patients with onchocerciasis were treated with diethylcarbamazine: a single course of treatment led to clinical cure in 48% of the patients; no means of anticipating which patients might require only a single course of treatment was found.
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Topical diethylcarbamazine in ocular onchocerciasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1973Abstract 1. 1. The effects of 3% diethylcarbamazine eye drops (Onchozan) on O. volvulus microfilariae in the cornea and in the anterior chamber are described in 9 Cameroonian subjects. 2. 2. The therapy tended to reduce the numbers of microfilariae seen in the anterior chamber, but they were not completely eliminated.
J, Anderson, H, Fuglsang
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Respiratory mechanics after chronic diethylcarbamazine
Respiration Physiology, 1997This study was performed to evaluate the role of diethylcarbamazine (DEC), the drug of choice for treating Lymphatic Filariasis and Tropical Pulmonary Eosinophilia, on respiratory mechanics of higid rats. Thus, during 30 days two groups of six rats each received intraperitoneally either isotonic saline solution, or 12 mg/kg per day of DEC.
S T, Aires +5 more
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Identification and quantification of diethylcarbamazine and diethylcarbamazineN-oxide in rat urine
Xenobiotica, 19811. Diethylcarbamazine and its major metabolite, diethylcarbamazine N-oxide have been identified and quantified in the urine of rats dosed orally with [14C]diethylcarbamazine citrate.2. The urinary excretion of diethylcarbamazine N-oxide as percentage of dose was not dose-dependent.3. These observations are in agreement with previous studies.
G, Edwards +3 more
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Analysis of diethylcarbamazine and diethylcarbamazine-N-oxide by gas chromatography
Archives of Pharmacal Research, 1996Diethylcarbamazine (DEC, 1-diethylcarbamyl-4-methylpiperazine) is an antiparasitic piperazine derivative used in the treatment of lymphatic filariasis caused byWuchereria bancrofti, Brugia malayi orBrugia timori. DEC-N-oxide is a major metabolite in humans and has antifilarial activity.
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