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The widely used diethylhexyl phthalate (DEHP) is a known endocrine disruptor that causes persistent alterations in the structure and function of female reproductive system, including ovaries, uterus and oviducts. To explore the molecular mechanism of the effect of DEHP on the development of mammary glands, we investigated the cell cycle, growth ...
Li, L. +9 more
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Kinetics of diethylhexyl‐phthalate extraction From polyvinylchloride‐infusion lines
Journal of Parenteral and Enteral Nutrition, 2002BACKGROUND: For infusion therapy, polyvinylchloride (PVC)‐infusion lines are commonly used. In this study, we examined the temperature dependency and the dynamics of extraction in the time course of infusion. METHODS: PVC‐infusion lines used on the newborn ICU were perfused with a typical 24‐hour fat infusion.
Steffan, Loff +5 more
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Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice
Molecular Biology Reports, 2013We previously demonstrated that the effects of diethylhexyl phthalate (DEHP) alter reproduction function on male mice. Immature male mice were treated daily with DEHP from postnatal day 7-21, 7-35, 7-49, in a dose-dependent manner. As results, both the quality and quantity of spermatozoa were decreased in 60-day-old mice. The results by RT-PCR analysis
Xi-Feng, Zhang +9 more
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Diethylhexyl phthalate as a factor in blood tranfusion and haemodialysis
Toxicology, 1978Di-2-ethylhexyl phthalate (DEHP), the most frequently occurring plasticiser in medical equipment manufactured from polymers of vinyl chloride, forms about 40% w/w of tubes and containers used for storing blood and for haemodialysis. The plasticiser leaches out into liquids with lipid contents, although it is very sparingly soluble in purely aqueous ...
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Kinetic Migration of Diethylhexyl Phthalate in Functional PVC Films
Plasma Science and Technology, 2012Plasticizers that are generally used in plastics to produce flexible food packaging materials have proved to cause reproductive system problems and women's infertility. A long-term consumption may even cause cancer diseases. Hence a nano-scale layer, named as functional barrier layer, was deposited on the plastic surface to prevent plasticizer ...
Fei Fei +3 more
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1987
Administration of the widely used plasticizer di(2-ethylhexyl)phthalate (2% w/w) in the diet to the rat caused proliferation of mitochondria in the liver. The number of mitochondria as well as the amount of protein recovered in the organellar fraction was doubled.
Nair, Nandini, Kurup, Ramakrishna CK
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Administration of the widely used plasticizer di(2-ethylhexyl)phthalate (2% w/w) in the diet to the rat caused proliferation of mitochondria in the liver. The number of mitochondria as well as the amount of protein recovered in the organellar fraction was doubled.
Nair, Nandini, Kurup, Ramakrishna CK
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Leaching of diethylhexyl phthalate from multilayer tubing into etoposide infusion solutions
American Journal of Health-System Pharmacy, 2005The extent of leaching of diethylhexyl phthalate (DEHP) from various polyvinyl chloride (PVC), polyethylene (PE), coextruded (PVC and PE), and triple-layered (PVC, ethyl vinyl acetate, and PE) i.v. extension tubing into etoposide infusion solutions was studied.Different lengths of tubing (25, 50, and 80 cm) were tested in two types of experiments: (1 ...
Sandrine, Bagel-Boithias +5 more
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Five‐day storage of platelets in a non‐diethylhexyl phthalate‐plasticized container
Transfusion, 1992A non‐diethylhexyl phthalate (DEHP)‐plasticized blood bag for 5‐day storage of random‐donor platelet concentrates has been developed. The plastic bag is composed of polyvinylchloride plastic with a butyryl trihexyl citrate plasticizer. The suitability of this plastic for the storage of platelet concentrates for use in clinical transfusion practice was ...
E L, Snyder +8 more
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Biopolyurethane/Diethylhexyl Phthalate Hybrid Plasticizer for Flexible Polyvinyl Chloride
Fibers and Polymers, 2020Worldwide concerns on the endocrine disruption of phthalate derivatives have sparked extensive research on its alternatives. One of the most prominent use of phthalate derivatives are on the plasticization of polyvinyl chloride (PVC). Therefore, numerous carboxyl acids and their derivates have been studied as candidates for PVC plasticizer. Elastomeric
Chang Kyu Park +2 more
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Diethylhexyl phthalate induces immune dysregulation and is an environmental immune disruptor
Journal of Hazardous MaterialsDiethylhexyl phthalate (DEHP) is the most abundant phthalate compound in the environment, and has been linked with multiple human diseases. The immune system is closely associated with the occurrence and progression of various diseases. However, minimal research has addressed the impact of DEHP on the immune system.
Dongli, Linghu +9 more
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