Association of diethylhexyl phthalate exposure with serum thyroid hormone levels: a systematic review and meta-analysis. [PDF]
Am J Transl ResOBJECTIVE Evidence suggests that diethylhexyl phthalate (DEHP) may disrupt thyroid hormone homeostasis by targeting multiple components of the hypothalamic-pituitary-thyroid (HPT) axis, potentially harming human health.
Xu K +5 more
europepmc +2 more sources
Environmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice [PDF]
mSystems, 2019 Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis and linked to chronic diseases and developmental disorders.
Ming Lei +7 more
doaj +4 more sources
Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans. [PDF]
PLoS Genet, 2020 Exposure to diethylhexyl phthalate (DEHP), the most abundant plasticizer used in the production of polyvinyl-containing plastics, has been associated to adverse reproductive health outcomes in both males and females.
Cuenca L +7 more
europepmc +2 more sources
Diethylhexyl phthalate induces teratogenic effects through oxidative stress response in a chick embryo model. [PDF]
Toxicol Res (Camb), 2020 Diethylhexyl phthalate (DEHP) is known as a persistent environmental pollutant. However, the possible effects of DEHP on human neural tube defects (NTDs) remain elusive.
Song G +6 more
europepmc +2 more sources
THE POTENTIAL OF DIETHYLHEXYL-PHTHALATE AND GENISTEIN TO INDUCE TESTICULAR CHANGES IN RAT'S OFFSPRING. [PDF]
Acta Endocrinol (Buchar), 2017 To study the effect of diethylhexyl phthalate (DEHP) alone or in combination with genistein (GEN) on the reproductive system of offspring rats, focus on the induction of reproductive outcomes.180 Wistar rats were divided in 6 groups (30 animals per group): DEHP 250 mg/kg/day group, DEHP 1000 mg/kg/day group, DEHP 2500 mg/kg/day group treated with DEHP ...
Li K, Wang R, Duan R, Liu Y.
europepmc +4 more sources
Independent and combined effects of diethylhexyl phthalate and polychlorinated biphenyl 153 on sperm quality in the human and dog. [PDF]
Sci Rep, 2019 A temporal decline in human and dog sperm quality is thought to reflect a common environmental aetiology. This may reflect direct effects of seminal chemicals on sperm function and quality.
Sumner RN +4 more
europepmc +2 more sources
Association Between Di-(2-Ethylhexyl) Phthalate and Childhood Asthma Through Plasma Metabolome Alterations. [PDF]
AllergyAllergy, Volume 81, Issue 1, Page 304-306, January 2026.
Kim MJ +21 more
europepmc +2 more sources
Emission characteristics of diethylhexyl phthalate (DEHP) from building materials determined using a passive flux sampler and micro-chamber. [PDF]
PLoS ONE, 2019 Emission rates of diethylhexyl phthalate (DEHP) from building materials, such as vinyl floorings and wall paper, determined using a passive flux sampler (PFS) were constant over the week-long measurement period.
Naohide Shinohara +3 more
doaj +2 more sources
Removal of Diethylhexyl Phthalate from Hands by Handwashing: Evidence from Experimental N-of-1 and Crossover Designs [PDF]
Scientific Reports, 2017 Phthalate exposure through skin is often neglected due to the small quantity and limited dermal absorption rate. However, free phthalate can be ingested by hand-to-mouth action or by contact with food.
Pi-I. D. Lin +5 more
doaj +2 more sources
Ecotoxicology and Environmental Safety, 2019 Epidemiological studies have shown that high molecular weight phthalates (HMW) such as diethylhexyl phthalate (DEHP), are associated with hypertension in humans, while low molecular weight phthalates (LMW) such as dibutyl phthalate (DBP), have hardly any impact on the elevation of blood pressure.
Xiaoman, Xie +5 more
openaire +3 more sources