DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption [PDF]
Endocrinology and Metabolism, 2021 Background Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland.
Min Joo Kim +7 more
doaj +1 more source
Phthalate exposure and childhood obesity [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Phthalates are commonly used as plasticizers and vehicles for cosmetic ingredients. Phthalate metabolites have documented biochemical activity including activating peroxisome proliferator-activated receptor and antiandrogenic effects, which may ...
Shin Hye Kim, Mi Jung Park
doaj +1 more source
Release of phthalate esters in pasteurized milk samples with plastic packaging
International Journal of Environmental Health Engineering, 2020 Aim: In this study, the presence of four phthalate esters, including diethyl phthalate (DEP), Dibutyl phthalate, benzyl butyl phthalate (BBP), and diethylhexyl phthalate (DEHP) in pasteurized milk with plastic packages was investigated during the time ...
Fatemeh Moradian +3 more
doaj +1 more source
Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance. [PDF]
J Toxicol Environ Health B Crit Rev, 2018 Male reproductive alterations found in animals and humans following in utero phthalate exposure include decreased anogenital distance (AGD) and other reproductive-tract malformations.
Dorman DC +12 more
europepmc +2 more sources
RISK21: risk analyzing tool on dietary exposure of phthalic acid esters
Zhongguo shipin weisheng zazhi, 2020 Objective To analyze the risks of dietary exposure of diethylhexyl phthalate (DEHP), dibutyl phthalate (DBP), diisononyl phthalate (DINP), butylbenzyl phthalate (BBP), diisobutyl phthalate (DIBP), dimethyl phthalate (DMP) and diethyl phthalate (DEP) to 2-
Huihui BAO +5 more
doaj +1 more source
Environment International, 2020 Many hazardous substances can be released during incineration of municipal solid waste (MSW), which pose a potential threat to human health. As additives, phthalates (PAEs) and bisphenols (BPs), which are widely used in daily goods, are likely to be ...
Shaoyou Lu +7 more
doaj +1 more source
In utero exposure to di(n-butyl) phthalate and testicular dysgenesis:comparison of fetal and adult end points and their dose sensitivity [PDF]
, 2007 BACKGROUND: Fetal exposure of male rats to di(n-butyl) phthalate (DBP) induces reproductive disorders similar to those in human testicular dysgenesis syndrome (TDS), including infertility, cryptorchidism, focal "dysgenetic areas," and Sertoli cell-only ...
Mahood, I. Kim +11 more
core +1 more source
Taxanes – The backbone of medical oncology
Indian Journal of Medical and Paediatric Oncology, 2020 Drug development in oncology has witnessed a revolutionary growth from its humble beginning with nitrogen mustard in 1940 to immunotherapy in 1986 (Interferon alpha).
Wesley M Jose
doaj +1 more source
Serum phthalate levels and time to pregnancy in couples from Greenland, Poland and Ukraine. [PDF]
PLoS ONE, 2015 Phthalates are ubiquitous industrial chemicals that have been associated with altered reproductive function in rodents. Several human studies have reported an inverse association between male testosterone and phthalate levels.
Ina Olmer Specht +5 more
doaj +1 more source
, 2010 BACKGROUND: The modulation of energetic homeostasis by pollutants has recently emerged as a potential contributor to the onset of metabolic disorders.
Gelman, Laurent +10 more
core +2 more sources