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Prenatal Exposure to Diethylhexyl Phthalate Impairs the Recovery of Spatial Memory Post-traumatic Brain Injury in a Sex-specific Manner

, 2022
Background Diethyl hexyl phthalate (DEHP) is a chemical plasticizer that causes significant neurological impairments after prenatal exposure. The impact of these exposures on cognitive recovery after severe traumatic brain injury (sTBI) has never been
M. Sun   +7 more
semanticscholar   +1 more source

Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice

Molecular Biology Reports, 2013
We previously demonstrated that the effects of diethylhexyl phthalate (DEHP) alter reproduction function on male mice. Immature male mice were treated daily with DEHP from postnatal day 7-21, 7-35, 7-49, in a dose-dependent manner. As results, both the quality and quantity of spermatozoa were decreased in 60-day-old mice. The results by RT-PCR analysis
Xi-Feng, Zhang   +9 more
openaire   +2 more sources

Portulaca Oleracea L. Phenolic Amide Methyl (3,4,5-Trimethoxybenzoyl) Valylprolinate Attenuates Diethylhexyl Phthalate-Induced Human Umbilical Vein Endothelial Cells’ Inflammation Through NLRP3 and NF-κB Pathways

Journal of Medicinal Food
Twelve polyphenol derivatives were obtained in a protective activity-guided isolation from the Portulaca oleracea L. extract on a cell model of human umbilical vein endothelial cells (HUVECs) under diethylhexyl phthalate (DEHP) exposure.
FanLi Bu   +6 more
semanticscholar   +1 more source

Migration of diethylhexyl phthalate from PVC bags into intravenous cyclosporine solutions

Journal of Pharmaceutical and Biomedical Analysis, 2005
The migration of diethylhexyl phthalate (DEHP) from PVC bags into LVPS (0.9% NaCl) and LVPS with cyclosporine at concentrations of 2.5 and 0.5mg/ml was studied. PVC bags were placed in contact with these solutions and stored at 25+/-1 degrees C. They were taken for analysis each 30 min during 6 h and after this period at each 1 h until 12 h of contact.
Gotardo, M. A., Monteiro, Magali
openaire   +3 more sources

Diethylhexyl phthalate exposure amplifies oxidant and inflammatory response in fetal hyperglycemia model predisposing insulin resistance in zebrafish embryos

Toxicology and industrial health
Exposure of zebrafish embryos to glucose is a suitable model for the fetal hyperglycemia seen in gestational diabetes. Diethylhexyl phthalate (DEHP), which is considered an endocrine-disrupting chemical, is one of the most common phthalate derivatives ...
G. Kaplan   +8 more
semanticscholar   +1 more source

Transgenerational inheritance of ovarian development deficiency induced by maternal diethylhexyl phthalate exposure

Reproduction, Fertility and Development, 2014
Diethylhexyl phthalate (DEHP) is a widely used industrial additive for increasing plastic flexibility. It disrupts the physiological functions of endogenous hormones and induces abnormal development of mammals. The objectives of the present study were to evaluate the effects of DEHP exposure on ovarian development of pregnant mice and whether the ...
Xi-Feng, Zhang   +7 more
openaire   +2 more sources

Diethylhexyl phthalate (DEHP) emission to indoor air and transfer to house dust from a PVC sheet.

Science of the Total Environment, 2020
Diethylhexyl phthalate (DEHP) emission to air and transfer to house dust from a polyvinyl chloride (PVC) sheet were quantified for periods of 1, 3, 7, and 14 days using a passive flux sampler (PFS).
N. Shinohara, K. Uchino
semanticscholar   +1 more source

Diethylhexyl phthalate as a factor in blood tranfusion and haemodialysis

Toxicology, 1978
Di-2-ethylhexyl phthalate (DEHP), the most frequently occurring plasticiser in medical equipment manufactured from polymers of vinyl chloride, forms about 40% w/w of tubes and containers used for storing blood and for haemodialysis. The plasticiser leaches out into liquids with lipid contents, although it is very sparingly soluble in purely aqueous ...
openaire   +2 more sources

Leaching of diethylhexyl phthalate from polyvinyl chloride bags into intravenous etoposide solution

Journal of Clinical Pharmacy and Therapeutics, 2002
To compare the release of diethylhexyl phthalate (DEHP) from polyvinyl chloride (PVC) bags from four different manufacturers into intravenous etoposide solutions.Etoposide solutions, 0.4 mg/mL, containing the vehicle polysorbate 80 were prepared in 5% dextrose or 0.9% sodium chloride injection PVC bags and stored at room temperature for 24 h.
B, Demoré   +4 more
openaire   +2 more sources

Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio): Altered microbial diversity, functionality, and network connectivity.

Environmental Pollution, 2020
Microbiome community structure is intimately involved in key biological functions in the gastrointestinal (GI) system including nutrient absorption and lipid metabolism.
Amanda N. Buerger   +6 more
semanticscholar   +1 more source

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