Results 41 to 50 of about 37,112 (220)

Taxanes – The backbone of medical oncology

open access: yesIndian Journal of Medical and Paediatric Oncology, 2020
Drug development in oncology has witnessed a revolutionary growth from its humble beginning with nitrogen mustard in 1940 to immunotherapy in 1986 (Interferon alpha).
Wesley M Jose
doaj   +1 more source

Diethylhexyl phthalates is associated with insulin resistance via oxidative stress in the elderly: a panel study. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Insulin resistance (IR) is believed to be the underlying mechanism of metabolic syndrome and type 2 diabetes mellitus (DM). Recently, a few studies have demonstrated that phthalates could cause oxidative stress which would contribute to the ...
Jin Hee Kim   +4 more
doaj   +1 more source

Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism [PDF]

open access: yes, 2016
Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during development.
A Giwercman   +60 more
core   +1 more source

Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors

open access: yesFEBS Letters, Volume 596, Issue 24, Page 3107-3123, December 2022., 2022
In this review, we describe endocrine disruptor (ED)‐related alterations in tissues involved in metabolic homeostasis, that is, adipose tissue, liver, pancreas, intestine and brain. We also present epigenetic effects of EDs. Finally, we propose an integrative view of multi‐organ alterations that explain how EDs can contribute to the development of ...
Kévin Bernal   +22 more
wiley   +1 more source

Plastisol Foaming Process. Decomposition of the Foaming Agent, Polymer Behavior in the Corresponding Temperature Range and Resulting Foam Properties [PDF]

open access: yes, 1998
The decomposition of azodicarbonamide, used as foaming agent in PVC - plasticizer (1/1) plastisols was studied by DSC. Nineteen different plasticizers, all belonging to the ester family, two being polymeric (polyadipates), were compared.
Abbiendi, G   +424 more
core   +3 more sources

Serum phthalate levels and time to pregnancy in couples from Greenland, Poland and Ukraine. [PDF]

open access: yesPLoS ONE, 2015
Phthalates are ubiquitous industrial chemicals that have been associated with altered reproductive function in rodents. Several human studies have reported an inverse association between male testosterone and phthalate levels.
Ina Olmer Specht   +5 more
doaj   +1 more source

Endocrine Disruption: Structural Interactions of Androgen Receptor against Di(2-ethylhexyl) Phthalate and Its Metabolites

open access: yesToxics, 2020
Diethylhexyl phthalate (DEHP) is a commonly used plasticizer in the manufacture of polyvinyl chloride plastics for household and commercial use. DEHP is a ubiquitous ecocontaminant and causes developmental and reproductive problems in children and adults.
Mohd Amin Beg, Ishfaq Ahmad Sheikh
doaj   +1 more source

Phthalate exposure and risk of ovarian dysfunction in endometriosis: human and animal data

open access: yesFrontiers in Cell and Developmental Biology, 2023
Objective: We aimed to explore the correlations between and possible mechanisms of common environmental endocrine disruptors, phthalates, and ovarian dysfunction in endometriosis.Methods: Subjects were included in the case group (n = 107) who were ...
Huan Yi   +8 more
doaj   +1 more source

Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance. [PDF]

open access: yes, 2006
Phthalate diesters have been shown to be developmental and reproductive toxicants in animal studies. A recent epidemiologic study showed certain phthalates to be significantly associated with reduced anogenital distance in human male infants, the first ...
Axelrad, Daniel   +4 more
core   +2 more sources

Diethylhexyl phthalate as a current problem of hygienic safety of packaging and packaged drinking water

open access: yesHygiene and Sanitation, 2022
Introduction. The chemical safety of packaged drinking water is influenced by many factors, including the quality of packaging materials. The chemical components included in the packaging can migrate into drinking water and have a negative impact on ...
E. Zaritskaya   +4 more
semanticscholar   +1 more source

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