Flutamide-induced hypospadias in rats: A critical assessment. [PDF]
This paper provides the first detailed description of flutamide-induced hypospadias in the rat based upon wholemount, histologic, three-dimensional reconstruction, scanning electron microscopic, and immunocytochemical analysis.
Baskin, Laurence +4 more
core +2 more sources
Distribution of Orally Administered Diethylhexyl Phthalate in Laying Hens
Abstract The distribution of diethylhexyl phthalate (DEHP) administered to laying hens has been investigated. DEHP administered orally was detected in almost all organs and tissues of the laying hens. An especially high level of concentration was present in the adipose tissues and feathers. The shift of DEHP from skin to feather was suggested.
M, Ishida +3 more
openaire +2 more sources
Evidence suggesting that di-n-butyl phthalate has anti-androgenic effects in fish [PDF]
This article is the pre-print version of the full and final published article.Phthalate ester plasticizers are anti-androgenic in mammals. High doses of certain phthalates consistently interfere with the normal development of male offspring exposed in ...
Adams +39 more
core +1 more source
A method validation for simultaneous determination of phthalates and bisphenol A released from plastic water containers [PDF]
Phthalates (or phthalate esters, PAEs) and bisphenol A (BPA) are widely used in various industries, particularly in the fields of cosmetics and packaging, and they increase the malleability and workability of materials.
Avino, P. +4 more
core +1 more source
An integrated approach combining chemical analysis and an in vivo bioassay to assess the estrogenic potency of a municipal solid waste landfill leachate in Qingdao. [PDF]
Various adverse effects related to landfill leachate have made leachates an important issue in past decades, and it has been demonstrated that landfill leachate is an important source of environmental estrogens.
Yufeng Gong +4 more
doaj +1 more source
Urine Phthalate Levels Before and after 2011 Diethylhexyl Phthalate Incident in Taiwan
Background: In 2011, Taiwan FDA accidentally discovered that manufacturers replaced expensive natural emulsifiers (palm oil) with diethylhexyl phthalate (DEHP) in numerous food products for decades...
I-Jen Wang* +2 more
openaire +1 more source
Prostaglandins, masculinization and its disorders:effects of fetal exposure of the rat to the cyclooxygenase inhibitor- indomethacin [PDF]
Recent studies have established that masculinization of the male reproductive tract is programmed by androgens in a critical fetal ‘masculinization programming window’ (MPW).
A Dean +34 more
core +8 more sources
Reproductive and developmental effects of phthalate diesters in females. [PDF]
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina +2 more
core +1 more source
Association of Urinary Concentrations of Bisphenol A and Phthalate Metabolites with Risk of Type 2 Diabetes: A Prospective Investigation in the Nurses’ Health Study (NHS) and NHSII Cohorts [PDF]
Background: Prospective evidence regarding associations for exposures to bisphenol A (BPA) and phthalates with type 2 diabetes (T2D) is lacking. Objective: We prospectively examined urinary concentrations of BPA and phthalate metabolites with T2D risk ...
Cornelis, Marilyn C. +7 more
core +1 more source
Multiple exposures to indoor contaminants: Derivation of benchmark doses and relative potency factors based on male reprotoxic effects [PDF]
International audienceSemi-Volatile Organic Compounds (SVOCs) are commonly present in dwellings and several are suspected of having effects on male reproductive function mediated by an endocrine disruption mode of action.
Bonvallot, Nathalie +5 more
core +3 more sources

