Results 141 to 150 of about 12,555 (220)

Blocking interleukin-1 receptor type 1 (IL-1R1) signaling in hepatocytes slows down diethylnitrosamine-induced liver tumor growth in obese mice. [PDF]

Hepatol Commun
Gehrke N, Hofmann LJ, Straub BK, Ridder DA, Waisman A, Kaps L, Galle PR, Schattenberg JM.   +7 more
europepmc   +1 more source

Carbohydrate-Responsive Element-Binding Protein-Associated Metabolic Changes in Chemically Induced Hepatocarcinogenesis Mouse Model. [PDF]

Int J Mol Sci
Engeler M, Karim M, Gischke M, Willer F, Leiner H, Prey J, Ziegler PF, Dombrowski F, Ribback S.   +8 more
europepmc   +1 more source

Chemopreventive Effects of Bioactive Peptides Derived from Black Soldier Fly Larvae Protein Hydrolysates in a Rat Model of Early-Stage Colorectal Carcinogenesis. [PDF]

Int J Mol Sci
Praseatsook K, Vachiraarunwong A, Sato K, Dissook S, Wanibuchi H, Taya S, Wongpoomchai R, Dejkriengkraikul P, Gi M, Yodkeeree S.   +9 more
europepmc   +1 more source

Therapeutic Potential of Hongjam in A Diethylnitrosamine and Thioacetamide-induced Hepatocellular Carcinoma Mouse Model. [PDF]

J Cancer Prev
Han YM, Ahn HR, Lee DY, Song MY, Lee SW, Jang YK, Jeon BY, Kim EH.   +7 more
europepmc   +1 more source

Glutathione and Selenium Supplementation Attenuates Liver Injury in Diethylnitrosamine-Induced Hepatocarcinogenic Mice by Enhancing Glutathione-Related Antioxidant Capacities. [PDF]

Int J Mol Sci
Hsiao YF, Huang SC, Cheng SB, Hsu CC, Huang YC.   +4 more
europepmc   +1 more source

Thai Fermented Soybean (Thua-Nao) Prevents Early Stages of Colorectal Carcinogenesis Induced by Diethylnitrosamine and 1,2-Dimethylhydrazine Through Modulations of Cell Proliferation and Gut Microbiota in Rats. [PDF]

Nutrients
Taya S, Dissook S, Ruangsuriya J, Yodkeeree S, Boonyapranai K, Chewonarin T, Wongpoomchai R.   +6 more
europepmc   +1 more source

Reinterpreting the True Cause and Nature of Unexpected Liver Lumps. [PDF]

Am J Pathol
Michalopoulos GK.
europepmc   +1 more source

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Diethylnitrosamine-induced liver tumorigenesis in mice

Methods in Cell Biology, 2021
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third leading cause of cancer related mortality with a 10 year survival rate of merely 22-35%. Tumorigenesis frequently occurs in patients with chronic liver disease where continued liver cell damage, compensatory proliferation and inflammation provide the basis for tumor ...
Isabel, Schulien, Peter, Hasselblatt
openaire   +3 more sources

Diethylnitrosamine Induction of Hepatocarcinogenesis in Mice

Methods in molecular biology
Diethylnitrosamine (DEN) is a chemical hepatocarcinogenic agent that triggers a large array of oncogenic mutations after a single injection. Initiated hepatocytes subsequently undergo clonal expansion within a proliferative environment, rendering the DEN model a comprehensive carcinogen.
Jules, Sotty, Pierre, Bablon, Paul-Henry, Weiss, Patrick, Soussan   +3 more
openaire   +3 more sources

Protective effect of rosemary (Rosmarinus officinalis) against diethylnitrosamine-induced renal injury in rats

Biomarkers, 2020
Context: The kidney plays a central role in detoxification and excretion of toxic metabolites, and therefore, is susceptible to toxicity by xenobiotics.
Mariam Abdur-Rahman, Abdelgawad Fahmi, Engy Shams-Eldin   +2 more
exaly   +2 more sources