Results 111 to 120 of about 6,519,461 (316)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Zwierzęce, jakiego nie ma

Zoophilologica, 2015
The text constitutes an attempt to discuss the idea of the “animal” itself, which is an empty set. Following Jacques Derrida’s line of thought, we remain surprised, asking what links the elephant with the ant or the echidna with the hedgehog.
Beata Mytych-Forajter
doaj  

Analysis of differences between 99mTc-MAA SPECT- and 90Y-microsphere PET-based dosimetry for hepatocellular carcinoma selective internal radiation therapy [PDF]

, 2019
Marilyne Kafrouni, Carole Allimant, Marjolaine Fourcade, Sébastien Vauclin, Boris Guiu, Denis Mariano‐Goulart, Fayçal Ben Bouallègue   +6 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

DRAMATIC DIFFERENCE IN DIVERSITY BETWEEN PLASMODIUM FALCIPARUM AND PLASMODIUM VIVAX RETICULOCYTE BINDING-LIKE GENES [PDF]

, 2005
Julian C. Rayner, Tuan M. Tran, Vladimir Corredor, Curtis S. Huber, John W. Barnwell, Mary R. Galinski   +5 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The Affective Biopolitics of Migration

Nordic Journal of Migration Research, 2019
Mons Bissenbakker, Lene Myong
doaj   +1 more source

Racial/Ethnic and Socioeconomic Differences in Short-Term Breast Cancer Survival Among Women in an Integrated Health System

, 2015
Theresa H.M. Keegan, Allison W. Kurian, Kathleen Gali, Tao Li, Daphne Y. Lichtensztajn, Dawn L. Hershman, Laurel A. Habel, Bette J. Caan, Scarlett Lin Gomez   +8 more
openalex   +1 more source

Think health: what makes the difference? [PDF]

, 1997
Ilona Kickbusch
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source