Results 111 to 120 of about 793,794 (302)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Eventually periodic solutions of a max-type difference equation. [PDF]

ScientificWorldJournal, 2014
Sun T, Liu J, He Q, Liu XH, Tao C.
europepmc   +1 more source

FINITE DIFFERENCE METHOD IMPLEMENTATION FOR NUMERICALINTEGRATION HYDRODYNAMIC EQUATIONS MELTS

, 2020
С. Ш. Кажикенова
openalex   +1 more source

Global Behavior of a Higher‐Order Difference Equation [PDF]

, 2010
Tuo Li, Xiumei Jia
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Beverton-Holt q-difference equation. [PDF]

J Biol Dyn, 2013
Bohner M, Chieochan R.
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Global dynamics of certain homogeneous second-order quadratic fractional difference equation. [PDF]

ScientificWorldJournal, 2013
Garić-Demirović M, Kulenović MR, Nurkanović M.   +2 more
europepmc   +1 more source

Linear 𝑞-difference equations [PDF]

Bulletin of the American Mathematical Society, 1931
openaire   +3 more sources

An error estimate for the finite difference approximation to degenerate convection -diffusion equations [PDF]

, 2011
Kenneth H. Karlsen, Ujjwal Koley, Nils Henrik Risebro   +2 more
openalex   +1 more source