Results 121 to 130 of about 4,949,896 (284)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Global Behavior of a Rational Difference Equation

open access: yes四川大学学报. 自然科学版, 2018
In this paper, we determine the forbidden set, introduce an explicit formula for the solutions, and discuss the global behavior of a rational difference equation x_(n+1)=(x_n x_(n-k))/(αx_n+βx_(n-(k+1)) ), where inter k∈N, inter n∈N∪{0},α,β are real ...
CHEN Wei-Wei
doaj  

Eventually periodic solutions of a max-type difference equation. [PDF]

open access: yesScientificWorldJournal, 2014
Sun T, Liu J, He Q, Liu XH, Tao C.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The Beverton-Holt q-difference equation. [PDF]

open access: yesJ Biol Dyn, 2013
Bohner M, Chieochan R.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Global dynamics of certain homogeneous second-order quadratic fractional difference equation. [PDF]

open access: yesScientificWorldJournal, 2013
Garić-Demirović M   +2 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Existence Results for Nonlinear Fractional Difference Equation

open access: yesAdvances in Difference Equations, 2011
This paper is concerned with the initial value problem to a nonlinear fractional difference equation with the Caputo like difference operator. By means of some fixed point theorems, global and local existence results of solutions are obtained.
Luo Xiannan, Zhou Yong, Chen Fulai
doaj  

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