Results 111 to 120 of about 3,599,122 (270)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Eventually periodic solutions of a max-type difference equation. [PDF]

open access: yesScientificWorldJournal, 2014
Sun T, Liu J, He Q, Liu XH, Tao C.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Beverton-Holt q-difference equation. [PDF]

open access: yesJ Biol Dyn, 2013
Bohner M, Chieochan R.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Existence Results for Nonlinear Fractional Difference Equation

open access: yesAdvances in Difference Equations, 2011
This paper is concerned with the initial value problem to a nonlinear fractional difference equation with the Caputo like difference operator. By means of some fixed point theorems, global and local existence results of solutions are obtained.
Luo Xiannan, Zhou Yong, Chen Fulai
doaj  

Global dynamics of certain homogeneous second-order quadratic fractional difference equation. [PDF]

open access: yesScientificWorldJournal, 2013
Garić-Demirović M   +2 more
europepmc   +1 more source

Linear 𝑞-difference equations [PDF]

open access: yesBulletin of the American Mathematical Society, 1931
openaire   +3 more sources

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