Results 121 to 130 of about 14,780,959 (374)

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Hirota’s difference equations [PDF]

open access: yesTheoretical and Mathematical Physics, 1997
A review of selected topics in Hirota's bilinear difference equation (HBDE) is given. This famous 3-dimensional difference equation is known to provide a canonical integrable discretization for most important types of soliton equations. Similarly to the continuous theory, HBDE is a member of an infinite hierarchy. The central point of our exposition is
openaire   +3 more sources

On the Difference Equation

open access: yes, 2011
We show that the difference equation , where , the parameters , and initial values , are real numbers, can be solved in closed form considerably extending the results in the literature.
C. Kent, W. Kosmala, S. Stević
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Oscillatory properties for Emden–Fowler type difference equations with oscillating coefficients

open access: yesResults in Applied Mathematics
In this paper, we give new criteria on the oscillation of the fourth-order Emden–Fowler type delay difference equation with oscillating coefficients of the form ΔWn+rnyn−τβ=0,n≥n0,where Wn=pnΔ3vnα and vn=yn+qnyn−σ.
Yaşar Bolat   +2 more
doaj   +1 more source

An explicit finite difference scheme for the Camassa-Holm equation

open access: yes, 2008
We put forward and analyze an explicit finite difference scheme for the Camassa-Holm shallow water equation that can handle general $H^1$ initial data and thus peakon-antipeakon interactions.
Coclite, Giuseppe Maria   +2 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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