Results 91 to 100 of about 118,141,604 (302)

A Rare Presentation of 17α-Hydroxylase/17,20-Lyase Deficiency in a Patient with Non-Hodgkin’s Lymphoma: A Case Report

JCRPE
17α‑hydroxylase/17,20‑lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia that causes decreased cortisol and sex steroid levels and leads to high production of adrenocorticotropic hormone.
Niran Tekkeli, İlknur Kurt, Nevin Yalman, Çetin Timur, Şenol Demir, Elif Sağsak   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Cause-specific contributions to sex differences in adult mortality among whites and African Americans between 1960 and 1995 [PDF]

The purpose of this paper is to describe trends in sex differences in mortality in young adulthood and in middle age among African Americans and whites in the United States between 1960 and 1995.
Greg L. Drevenstedt, Irma Elo
core  

Development Effectiveness Overview (DEO) 2020

, 2020
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Sex differences in umbilical artery Doppler indices: A longitudinal study [PDF]

, 2018
Background: Sexual dimorphism in placental size and function has been described. Whether this influences the clinically important umbilical artery (UA) waveform remains controversial, although a few cross-sectional studies have shown sex differences in ...
Wilsgaard, Tom, Ganesh Acharya, Kari Flo, Christian Widnes, Tom Wilsgaard, Widnes, Christian, Kiserud, Torvid, Acharya, Ganesh, Torvid Kiserud, Flo, Kari   +9 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Coronary artery calcification and aortic valve calcification in patients with kidney failure : a sex-disaggregated study

, 2023
Background: Chronic kidney disease (CKD) is linked to an increased cardiovascular disease (CVD) burden. Albeit underappreciated, sex differences are evident in CKD with females being more prone to CKD development, but males progressing more rapidly to ...
Ward, Liam J.,, Laucyte-Cibulskiene, Agne, Hernandez, Leah,, Ward, L, Hernandez, Leah, Ripsweden, Jonaz, Laucyte-Cibulskiene, Agne,, Ripsweden, Jonaz,, Ripsweden, J,, Kublickiene, Karolina, Laucyte-Cibulskiene, A, Stenvinkel, Peter,, Kublickiene, K,, Stenvinkel, Peter, Stenvinkel, P,, Lund University., Ward, Liam J., Hernandez, L, GOING-FWD Collaborators, Kublickiene, Karolina,   +19 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The emergence of cognitive sex differences during adolescence : a longitudinal study [PDF]

, 2009
Cognitive sex differences have consistently been found in adulthood, with males excelling on visual-spatial tasks and females excelling on manual dexterity tasks.
Hill, Heather H., NC DOCKS at The University of North Carolina Wilmington   +1 more
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