Results 71 to 80 of about 2,431,645 (337)

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism. [PDF]

, 2015
Several observations support the hypothesis that differences in synaptic and regional cerebral plasticity between the sexes account for the high ratio of males to females in autism. First, males are more susceptible than females to perturbations in genes
Duret, P., Forgeot d'Arc, B., Jacquemont, S., Moore, R.D., Mottron, L., Mueller, S., Xiong, L.   +6 more
core   +2 more sources

Birth Weight in Different Etiologies of Disorders of Sex Development [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2017
It is well established that boys are heavier than girls at birth. Although the cause of birth weight (BW) difference is unknown, it has been proposed that it could be generated from prenatal androgen action.The aim of the current study was to determine the BW of children with disorders of sex development (DSD) of different etiologies and to evaluate ...
Poyrazoglu, S., Darendeliler, F., Ahmed, S.F., Hughes, I., Bryce, J., Jiang, J., Rodie, M., Hiort, O., Hannema, S.E., Bertelloni, S., Lisa, L., Guran, T., Cools, M., Desloovere, A., Claahsen-van der Grinten, H.L., Claahsen-van der Grinten, H.L., Nordenstrom, A., Holterhus, P.M., Kohler, B., Niedziela, M., Krone, N.   +20 more
openaire   +8 more sources

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Ovotesticular differences of sex development: male or female? Case series

Italian Journal of Pediatrics, 2019
Background The choice of the sex of rearing in patients with ovotesticular differences of sex development (OT-DSD) is difficult. The final decision should be given by the patient himself or herself, but families’ opinion is not to neglect especially when
Maria-Grazia Scarpa, Arianna Lesma, Massimo Di Grazia, Waifro Rigamonti   +3 more
doaj   +1 more source

Influence of sex differences on microRNA gene regulation in disease. [PDF]

, 2014
Sexual dimorphism is observed in most human diseases. The difference in the physiology and genetics between sexes can contribute tremendously to the disease prevalence, severity, and outcome.
Eghbali, Mansoureh, Sharma, Salil
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Sex-dependent Depot Differences in Adipose Tissue Development and Function; Role of Sex Steroids

Journal of Obesity & Metabolic Syndrome, 2017
Men and women are different in their fat mass and distribution pattern. The gynoid-type fat distribution, accumulation in lower-body, is considered to be protective while the android-type accumulation in upper-body, both in abdominal subcutaneous and ...
Mi-Jeong Lee, Susan K. Fried
doaj   +1 more source

Influences on achieving motor milestones: A twin-singleton study [PDF]

, 2006
In order to determine if twinning impacted achievement of motor milestones the attainment of early motor milestones in twins was examined and compared to published data from singletons of the same age from the same culture and birth years.
Dorret I. Boomsma, James J. Hudziak, Jantz J. W., Livshits G., Luke B., Luke B., Meike Bartels, Morly R., Piper M. C., Ratliff-Schaub K., Salls J. S., Siegel A. C., Silvia I. Brouwer, Toos C. E. M. van Beijsterveldt   +13 more
core   +2 more sources

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source