Results 111 to 120 of about 18,357,557 (300)

High-temperature tolerance of Citrus maxima ‘Mansailong’ seeds at different developmental stages

Guangxi Zhiwu
The seeds are invariably exposed to high-temperature conditions since global warming frequently causes abnormally high temperature. In order to investigate the physiological basis of high-temperature tolerance in seeds, we used intermediate Citrus maxima
AN Xuejiao, YANG Lan, WEN Bin, CHEN Ligang   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Expression of the SET protein in testes of mice at different developmental stages

Asian Journal of Andrology, 2014
SET is a multifunctional protein involved in regulating many biological processes of the cell cycle. It is also a regulator of steroidogenesis in the ovary. However, the expression of SET protein in testis, and its function, still remains ambiguous. In this study, we observed the expression of SET in the testes of mice at different developmental stages,
Xiao-Nan Dai, Shan Liu, Li Shao, Chao Gao, Li Gao, Jia-Yin Liu, Yu-Gui Cui   +6 more
openaire   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Molecular Characterization and Expression Response Under Hypoxic-Reoxygenation Stress of a Crustacyanin-Like Gene in Procambarus clarkii

Progress in Fishery Sciences
Crustacyanin (CRCN), a family of lipocalin proteins specific to crustaceans, was primarily found in the exoskeleton of crustaceans. By binding with astaxanthin to form the astaxanthin-binding protein complex, it resets the proton at the end of ...
Yiming HAN, Suwan LU, Zhiqiang XU, Yu XU, Hai LIN, Jianlin PAN, Jiaxin YANG, Xuguang LI   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Summary of Gene Ontology (GO) terms for differentially expressed genes (DEGs) at different developmental stages (P < 0.05).

, 2016
Summary of Gene Ontology (GO) terms for differentially expressed genes (DEGs) at different developmental stages (P < 0.05).
Lixin An (2993121), Shanshan Liu (315561), Hongxiu Gao (2993109), Xue Zhao (76712), Xiaoshuang Wei (2993118), Hongbo Ren (2993115), Hari B. Krishnan (1630834), Bo Song (255492), Yanjing Han (2993112)   +8 more
core   +1 more source

Comparative analysis of transcriptomics of Fasciola hepatica at different developmental stages

Tropical Biomedicine
This study explored the transcriptome differences in Fasciola hepatica at different developmental stages and identified functional genes related to growth and development during juvenile stages. DNBSEQ eukaryotic strand-specific transcriptome resequencing technology was used to sequence the transcriptomes of Fasciola hepatica eggs, juveniles, and ...
N, Li, W, Tian, L, Sun, H, Yan, S, Hasi
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Schematic of the protocol used to collect the different developmental stages of C1A employed for the transcriptional study.

, 2016
Schematic of the protocol used to collect the different developmental stages of C1A employed for the transcriptional study.
Shelby Calkins (3185496), Noha H. Youssef (243149)   +1 more
core   +1 more source