Results 111 to 120 of about 13,324 (296)

On the differentiability of T(r,f)

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1982
It is well known that T(r,f) is differentiable at least for r>r0. We show that, in fact, T(r,f) is differentiable for all but at most one value of r, and if T(r,f) fails to have a derivative for some value of r, then f is a constant times a quotient of ...
Douglas W. Townsed
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Relation between differentiability and monotonicity of real functions

open access: yes
This thesis explores the intricate relationship between differentiability and monotonicity in real functions, two fundamental concepts in mathematical analysis.
Irin, Namira
core  

Differentiability of the Value Function

open access: yes, 1993
This paper characterizes the differentiability of the value function. We provide a characterization of the necessary and sufficient conditions for the differentiability of the value function.
Kim, Taesung
core  

A strong form of almost differentiability [PDF]

open access: yes, 2009
We present a uniformization of Reeken's macroscopic differentiability (see [5]), discuss its relations to uniform differentiability (see [6]) and classical continuous differentiability, prove the corresponding chain rule, Taylor's theorem, mean value ...
Almeida, R., Neves, V.
core  

Intermediate values and inverse functions on non-Archimedean fields

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
Continuity or even differentiability of a function on a closed interval of a non-Archimedean field are not sufficient for the function to assume all the intermediate values, a maximum, a minimum, or a unique primitive function on the interval.
Khodr Shamseddine, Martin Berz
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Fr échet Differentiability of Real-Valued Functions

open access: yes, 2012
This chapter shows that cone-monotone functions on Asplund spaces have points of Fréchet differentiability and that the appropriate version of the mean value estimates holds. It also proves that the corresponding point of Fréchet differentiability may be
Tiˇser Jaroslav   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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