Results 51 to 60 of about 1,809,735 (299)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Ergodic theory of generic continuous maps

, 2012
We study the ergodic properties of generic continuous dynamical systems on compact manifolds. As a main result we prove that generic homeomorphisms have convergent Birkhoff averages under continuous observables at Lebesgue almost every point. In spite of
Abdenur, Flávio, Andersson, Martin
core   +1 more source

Differentiable Likelihoods for Fast Inversion of 'Likelihood-Free'\n Dynamical Systems [PDF]

, 2020
Hans Kersting, Nicholas Krämer, Martin Schiegg, Christian Daniel, Michael Tiemann, Philipp Hennig   +5 more
openalex   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Bounds of Different Integral Operators in Tensorial Hilbert and Variable Exponent Function Spaces

Mathematics
In dynamical systems, Hilbert spaces provide a useful framework for analyzing and solving problems because they are able to handle infinitely dimensional spaces.
Waqar Afzal, Mujahid Abbas, Omar Mutab Alsalami   +2 more
doaj   +1 more source

Differential Dynamic Logic for Hybrid Systems

Journal of Automated Reasoning, 2008
AbstractHybrid systems are models for complex physical systems and are defined as dynamical systems with interacting discrete transitions and continuous evolutions along differential equations. With the goal of developing a theoretical and practical foundation for deductive verification of hybrid systems, we introduce a dynamic logic for hybrid ...
openaire   +1 more source

Extended Differential Balancing for Nonlinear Dynamical Systems

IEEE Control Systems Letters, 2022
In this paper, we construct extended balancing theory for nonlinear systems in the contraction framework. At first, we introduce the concept of the extended differential observability Gramian and inverse of the extended differential controllability Gramian for nonlinear dynamical systems and show their correspondence with generalized differential ...
Arijit Sarkar, Jacquelien M. A. Scherpen
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Dynamical Systems Method (DSM) for solving nonlinear operator equations in Banach spaces [PDF]

, 2010
Let $F(u)=h$ be an operator equation in a Banach space $X$, $\|F'(u)-F'(v)\|\leq \omega(\|u-v\|)$, where $\omega\in C([0,\infty))$, $\omega(0)=0$, $\omega(r)>0$ if $r>0$, $\omega(r)$ is strictly growing on $[0,\infty)$. Denote $A(u):=F'(u)$, where $F'(u)$
Ramm, A. G.
core   +7 more sources