Results 51 to 60 of about 1,833,044 (301)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
MathematicsThe present paper describes, in a theoretical fashion, a variational approach to formulate fourth-order dynamical systems on differentiable manifolds on the basis of the Hamilton–d’Alembert principle of analytic mechanics.
Simone Fiori
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Ergodic theory of generic continuous maps
, 2012 We study the ergodic properties of generic continuous dynamical systems on compact manifolds. As a main result we prove that generic homeomorphisms have convergent Birkhoff averages under continuous observables at Lebesgue almost every point. In spite of
Abdenur, Flávio, Andersson, Martin
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Differentiable Likelihoods for Fast Inversion of 'Likelihood-Free'\n Dynamical Systems [PDF]
, 2020 Hans Kersting +5 more
openalex +2 more sources
Bounds of Different Integral Operators in Tensorial Hilbert and Variable Exponent Function Spaces
MathematicsIn dynamical systems, Hilbert spaces provide a useful framework for analyzing and solving problems because they are able to handle infinitely dimensional spaces.
Waqar Afzal +2 more
doaj +1 more source
Dynamical Systems Method (DSM) for solving nonlinear operator equations in Banach spaces [PDF]
, 2010 Let $F(u)=h$ be an operator equation in a Banach space $X$, $\|F'(u)-F'(v)\|\leq \omega(\|u-v\|)$, where $\omega\in C([0,\infty))$, $\omega(0)=0$, $\omega(r)>0$ if $r>0$, $\omega(r)$ is strictly growing on $[0,\infty)$. Denote $A(u):=F'(u)$, where $F'(u)$
Ramm, A. G.
core +7 more sources
Can chaos be observed in quantum gravity?
, 2017 Full general relativity is almost certainly 'chaotic'. We argue that this entails a notion of nonintegrability: a generic general relativistic model, at least when coupled to cosmologically interesting matter, likely possesses neither differentiable ...
Dittrich, Bianca +3 more
core +1 more source