Results 111 to 120 of about 274,031 (283)

Asymptotic Behavior of Ground State Radial Solutions for -Laplacian Problems

Journal of Mathematics, 2013
Let , we take up the existence, the uniqueness and the asymptotic behavior of a positive continuous solution to the following nonlinear problem in , , , , where , is a positive differentiable function in and is a positive continuous function in such ...
Sonia Ben Othman, Rym Chemmam, Habib Mâagli   +2 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Some Formulas for Legendre Functions Induced by the Poisson Transform

Acta Polytechnica, 2011
Using the Poisson transform, which maps any homogeneous and infinitely differentiable function on a cone into a corresponding function on a hyperboloid, we derive some integral representations of the Legendre functions.
I. A. Shilin, A. I. Nizhnikov
doaj  

A review of differentiable digital signal processing for music and speech synthesis

Frontiers in Signal Processing
The term “differentiable digital signal processing” describes a family of techniques in which loss function gradients are backpropagated through digital signal processors, facilitating their integration into neural networks.
Ben Hayes, Jordie Shier, György Fazekas, Andrew McPherson, Charalampos Saitis   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

INFORMATIONAL ENTROPY IN SIMULATION OF ONE-DIMENSIONAL RANDOM FIELDS

TASK Quarterly, 2002
The entropy H of a continuous distribution with probability density function f(•) is defined as a function of the number of nodes (n) in a one-dimensional scalar random field.
SZYMON OPOKA, HENRYK WALUKIEWICZ
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Differentiable Functions Equivalent to Analytic Functions

Publications of the Research Institute for Mathematical Sciences, 1973
1. Let jf, g be real-valued functions of class C in R. Functions /, g are called equivalent if there exists a diffeomorphism (of class C°°) r of R such that f°t=g. The main object of this paper is to show under what conditions a function is equivalent to an analytic function (Theorem i). In the case of polynomials, the corresponding result is proved in
openaire   +2 more sources