Results 91 to 100 of about 1,173,776 (257)
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
FUZZY OSTROWSKI TYPE INEQUALITIES FOR (α,m)-CONVEX FUNCTIONS
− Let f : I → R, where I ⊆ R is an interval, be a mapping differentiable in the interiorI◦of I, and let a, b ∈ I◦with a < b. If |f0(x)| ≤ M for all x ∈ [a, b], then the following inequalityholds:¯ ¯ ¯f (x) −¯ ¯ b − a Z b a f (t)dt¯≤ M (b − a)¯ ¯ ¯ ¯ "
Erhan Set, Serkan Karataş, İlker Mumcu
doaj
Tasmania 1:25 000 series [cartographic material] /
Topographic map series with cadastral information. Relief shown by contours and spot heights. Depths shown by soundings.; "Tasmap."; Sheets of various eds.; Some sheets are issued by: Mapping Division, Department of Lands, Parks and Wildlife; Mapping ...
Tasmania. Lands Department Mapping Division.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Tennant Creek, Northern Territory [cartographic material] : Commonwealth topographic survey /
1st ed. Topographic map of Tennant Creek region, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
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RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Tobermory, Northern Territory [cartographic material] : Commonwealth topographic survey /
Provisional ed. Topographic map of Tobermorey region, Northern Territory, on sheet entitled Tobermory, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields
Australia. Division of National Mapping.
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Photo index ... New Guinea [cartographic material].
Photomosaic series of Papua New Guinea.; "This photo index is merely a copy of an assembly of air photographs and is not an accurate map."; "Names shown in red on this map have been supplied by C.S.I.R.O. Land Research Unit and are subject to approval by
Australia. Division of National Mapping.
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

