Results 91 to 100 of about 1,173,776 (257)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

FUZZY OSTROWSKI TYPE INEQUALITIES FOR (α,m)-CONVEX FUNCTIONS

open access: yesJournal of New Theory, 2015
− Let f : I → R, where I ⊆ R is an interval, be a mapping differentiable in the interiorI◦of I, and let a, b ∈ I◦with a < b. If |f0(x)| ≤ M for all x ∈ [a, b], then the following inequalityholds:¯ ¯ ¯f (x) −¯ ¯ b − a Z b a f (t)dt¯≤ M (b − a)¯ ¯ ¯ ¯ "
Erhan Set, Serkan Karataş, İlker Mumcu
doaj  

Tasmania 1:25 000 series [cartographic material] /

open access: yes, 1979
Topographic map series with cadastral information. Relief shown by contours and spot heights. Depths shown by soundings.; "Tasmap."; Sheets of various eds.; Some sheets are issued by: Mapping Division, Department of Lands, Parks and Wildlife; Mapping ...
Tasmania. Lands Department Mapping Division.
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Tennant Creek, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1958
1st ed. Topographic map of Tennant Creek region, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Tobermory, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1960
Provisional ed. Topographic map of Tobermorey region, Northern Territory, on sheet entitled Tobermory, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields
Australia. Division of National Mapping.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Photo index ... New Guinea [cartographic material].

open access: yes, 1956
Photomosaic series of Papua New Guinea.; "This photo index is merely a copy of an assembly of air photographs and is not an accurate map."; "Names shown in red on this map have been supplied by C.S.I.R.O. Land Research Unit and are subject to approval by
Australia. Division of National Mapping.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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