Results 91 to 100 of about 2,878,474 (274)

On the Correct Solvability of the Boundary-Value Problem for One Class Operator-Differential Equations of the Fourth Order with Complex Characteristics

open access: yesBoundary Value Problems, 2009
Sufficient coefficient conditions for the correct and unique solvability of the boundary-value problem for one class of operator-differential equations of the fourth order with complex characteristics, which cover the equations arising in solving the ...
Araz R. Aliev, Aydin A. Gasymov
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Functional differential equations with infinite delay in Banach spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
In this paper, a definition of the fundamental operator for the linear autonomous functional differential equation with infinite delay in a Banach space is given, and some sufficient and necessary conditions of the fundamental operator being ...
Jin Liang, Tijun Xiao
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Periodic solution for a delay integro-differential equation in biomathematics [PDF]

open access: yes, 2003
Sufficient conditions for the existence and uniqueness of periodic solution of a delay integro-differential equation which arise in biomathematics are given.
Bica, Alexandru Mihai, Muresan, Sorin
core   +3 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Bounded and multiperiodic solutions of the system of partial integro-differential equations

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
The system of partial integro - differential equations with an operator of differentiation with respect to directions of vector field is considered. The considering integro - differential equation does not contain space variables.
G.M. Aitenova   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Computable error bounds with improved applicability conditions for collocation methods

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1998
This paper is concerned with error bounds for numerical solution of linear ordinary differential equation using collocation method. It is shown that if the differential operator is split in different operator forms then the applicability conditions for ...
A. H. Ahmed
doaj   +1 more source

Home - About - Disclaimer - Privacy